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Las Vegas Raiders vs. Indianapolis Colts updated prediction featuring Ashton Jeanty, Jonathan Taylor [Week 5, 2025]
Get new expert Raiders vs Colts predictions for Sunday's game.

Dimers' latest NFL predictions are live for Indianapolis Colts and Las Vegas Raiders in Week 5, with our model giving the Colts a 71% of winning against the Raiders on Sunday.
This update builds on our early Colts-Raiders predictions, producing fresh win probabilities, score projections, and TD predictions for Ashton Jeanty, Jonathan Taylor, and more.
For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Raiders vs. Colts page.
What's changed? Las Vegas vs. Indianapolis updated predictions
Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Raiders vs. Colts matchup stacks up. Here are the updated forecasted:
- Straight Up Win Probabilities: Raiders 29%, Colts 71%
- Predicted Final Score: Raiders 20-26 Colts
- Spread: Raiders (+7) 60%, Colts (-7) 40%
- Total Points (47.5): Over 50%, Under 50%
As of October 2, 2025, these Raiders-Colts figures reflect changes since our early-week simulation.
Anytime touchdown scorer predictions
New NFL player projections for Week 5 highlight the top candidates to find the end zone in Raiders-Colts on Sunday:
Las Vegas Raiders
- Ashton Jeanty: 49.3% probability
- Jakobi Meyers: 27.2% probability
- Brock Bowers: 27.2% probability
Indianapolis Colts
- Jonathan Taylor: 59.0% probability
- Daniel Jones: 33.5% probability
- Tyler Warren: 31.1% probability
Raiders vs. Colts latest odds
The best current odds from the top sportsbooks in the US:
- Spread: Raiders +7 (-115), Colts -7 (-105)
- Moneyline: Raiders +265, Colts -300
- Total: Over/Under 47.5 (-115/-104)
Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.
Raiders vs. Colts Week 5 details
The NFL Week 5 action between the Colts and Raiders at Lucas Oil Stadium is scheduled for October 5, 2025.
- Who: Las Vegas Raiders vs. Indianapolis Colts
- Date: Sunday, October 5, 2025
- Time: 1:00PM ET/10:00AM PT
- Venue: Lucas Oil Stadium
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Conclusion
We predict the Colts, with a 71% win probability, will likely beat the Raiders in Week 5 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.
Enhanced by AI and automation, this article delivers quick, accurate insights on the Raiders vs. Colts game, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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