Clippers vs. Cavaliers prediction: Cleveland to win, Donovan Mitchell projected for big game in Sunday's NBA matchup [11/23/2025]

The Cleveland Cavaliers and Los Angeles Clippers are scheduled to meet in NBA action at Rocket Arena on Sunday, with tipoff at 6:00PM ET.

Based on updated simulations and today’s injury reports, Dimers' proven NBA model predicts the Cavaliers as the most likely winner of the Clippers vs. Cavaliers game.

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature players like Donovan Mitchell, Evan Mobley and Darius Garland, while the Clippers will look to James Harden, Kawhi Leonard and Ivica Zubac.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Clippers vs. Cavs prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Sunday's clash between the Clippers and Cavaliers.

Our independent predictive model currently gives the Cavaliers a 72% chance of beating the Clippers. Our predicted final score has the Cavaliers winning 117-111.

According to our model, the Clippers (+7.5) have a 52% chance of covering the spread, while the over/under total of 229.5 points has a 51% chance of staying under.

Clippers vs. Cavaliers odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Clippers vs. Cavaliers picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Sunday, the top play to make on this game is Clippers +7.5 at the spread.

Clippers vs. Cavaliers player props

Betting on Clippers vs. Cavaliers NBA player props? We use the best information available to project how each team's leading players will perform at Rocket Arena.

James Harden is expected to lead the Clippers with 23 points, 5 rebounds and 9 assists, while Donovan Mitchell is projected to have 27 points, 5 rebounds and 5 assists for the Cavaliers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Clippers prediction

Our model's projected player stats for the Clippers are:

Cavaliers prediction

Projected points, rebounds, assists and three-pointers made for the Cavaliers:

Clippers vs. Cavs game-day updates and essential details

Sunday's game between the Cavaliers and Clippers at Rocket Arena is scheduled to begin at 6:00PM ET.

• Who: Los Angeles Clippers vs. Cleveland Cavaliers
• Date: Sunday, November 23, 2025
• Time: 6:00PM ET/3:00PM PT
• Venue: Rocket Arena

Sports betting deal available for Missouri sports fans

To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that grants you $365 in bonus bets from a $10 bet — win or lose. Don't miss out!

Conclusion

We predict the Cavaliers, with a 72% win probability, will likely beat the Clippers on Sunday, with James Harden projected for a game-high 49 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Clippers vs. Cavaliers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.