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Clippers vs. 76ers prediction: Why Philadelphia is favored to win Monday's NBA matchup [11/17/2025]

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Written by Ryan Leaver

Get Los Angeles Clippers vs Philadelphia 76ers predictions for NBA Monday.

Los Angeles Clippers-Philadelphia 76ers Predictions and Game Preview.
Los Angeles Clippers vs. Philadelphia 76ers NBA prediction for Monday, November 17, 2025.

The Philadelphia 76ers and Los Angeles Clippers are scheduled to meet in NBA action at Xfinity Mobile Arena on Monday, with tipoff at 7:00PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the 76ers as the most likely winner of the Clippers vs. 76ers game.

This prediction follows the latest NBA Injury Report, which suggests the 76ers lineup will feature stars like Tyrese Maxey, Quentin Grimes and VJ Edgecombe, while the Clippers will rely on James Harden, Ivica Zubac and John Collins.

This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Sixers vs. Sixers prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Monday's clash between the Clippers and 76ers.

According to our model, the Clippers (+4.5) have a 53% chance of covering the spread, while the over/under total of 221.5 points has a 51% chance of staying under.

 

Clippers vs. 76ers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Clippers 76ers
Spread +4.5 (-105) -4.5 (-115)
Moneyline +166 -198
Total o221.5 (-114) u221.5 (-106)

All odds are correct at the time of publication and are subject to change.

Clippers vs. 76ers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Clippers +4.5 -105
Moneyline Clippers +166
Total Under 221.5 -106

According to our best NBA bets for Monday, the top play to make on this game is Clippers +4.5 at the spread.

 

Clippers vs. 76ers player props

Betting on Clippers vs. 76ers NBA player props? We have crunched the numbers to project how each team's leading players will perform at Xfinity Mobile Arena.

James Harden is expected to lead the Clippers with 25 points, 6 rebounds and 10 assists, while Tyrese Maxey is projected to have 26 points, 4 rebounds and 7 assists for the 76ers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Clippers prediction

Our model's projected player stats for the Clippers are:

Player PTS REB AST 3PM DFS
James Harden 25 6 10 4 55
Ivica Zubac 18 11 2 0 40
John Collins 17 7 2 1 34
B. Bogdanovic 12 4 4 2 26
Kobe Sanders 10 4 3 2 23

76ers prediction

Projected points, rebounds, assists and three-pointers made for the 76ers:

Player PTS REB AST 3PM DFS
Tyrese Maxey 26 4 7 3 47
Quentin Grimes 16 4 4 2 32
VJ Edgecombe 14 5 4 2 30
Paul George 13 4 3 2 27
Andre Drummond 12 12 2 0 36

Clippers vs. Sixers game-day updates and essential details

Monday's action between the 76ers and Clippers at Xfinity Mobile Arena is scheduled to commence at 7:00PM ET.

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Conclusion

We predict the 76ers, with a 65% win probability, will likely beat the Clippers on Monday, with James Harden projected for a game-high 55 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Clippers vs. 76ers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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