Loyola Chicago vs. St. Bonaventure prediction: St. Bonaventure favored to win men's college basketball matchup [1/20/2026]

St. Bonaventure will face Loyola Chicago in men's college basketball action at Reilly Center on Tuesday, beginning at 7:00 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts St. Bonaventure as the most likely winner of the Loyola Chicago vs. St. Bonaventure game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola Chicago vs. St. Bonaventure prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Tuesday's NCAA basketball game between Loyola Chicago and St. Bonaventure 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives St. Bonaventure an 86% chance of defeating Loyola Chicago. Our predicted final score has St. Bonaventure winning 79-67.

According to our model, the bookies have got it right, and Loyola Chicago and St. Bonaventure each have a 50% chance of covering the spread, while the over/under total of 147.5 points has a 51% chance of staying under.

Loyola Chicago vs. St. Bonaventure odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola Chicago vs. St. Bonaventure picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: