Men's college basketball picks today: Wednesday's best bets include Kansas State vs. Colorado play [2/25/2026]

Colorado -6.5 (-105)

• Edge: 8.3%
• Probability: 59.5%
• Matchup: Kansas State vs. Colorado (9:00PM ET, Wednesday)

Our model has identified value on Colorado -6.5 at -105 odds. A 59.5% probability produces an edge of 8.3%, making this the strongest play for today's men's college basketball slate.

Xavier vs. Providence under 170.5 points (-108)

• Edge: 5.7%
• Probability: 57.6%
• Matchup: Xavier vs. Providence (7:30PM ET, Wednesday)

Xavier vs. Providence under 170.5 points carries a 5.7% edge and a probability of 57.6% at -108 odds, according to our model.

George Mason vs. Saint Joseph's (PA) over 135.5 points (-110)

• Edge: 5.7%
• Probability: 58.1%
• Matchup: George Mason vs. Saint Joseph's (PA) (7:00PM ET, Wednesday)

George Mason vs. Saint Joseph's (PA) over 135.5 points at -110 odds shows a 5.7% edge, supported by a 58.1% probability in simulations.

American University ML (-300)

• Edge: 5.0%
• Probability: 80%
• Matchup: Lehigh vs. American University (7:00PM ET, Wednesday)

A 5.0% edge and 80% probability make American University at the moneyline at a value play in the Lehigh vs. American University matchup, per our model.

Nebraska-Omaha +1.5 (-125)

• Edge: 5.0%
• Probability: 60.5%
• Matchup: Nebraska-Omaha vs. South Dakota (7:00PM ET, Wednesday)

Nebraska-Omaha +1.5 at -125 odds presents a 5.0% edge, with simulations resulting in a probability of 60.5%.

Texas +7.5 (-110)

• Edge: 4.9%
• Probability: 57.3%
• Matchup: Florida vs. Texas (7:00PM ET, Wednesday)

Our model finds value on Texas +7.5 at -110 odds, supported by an edge of 4.9%.

Seattle -6.5 (-110)

• Edge: 4.9%
• Probability: 57.3%
• Matchup: Seattle vs. Pepperdine (9:00PM ET, Wednesday)

Our model has uncovered value on Seattle -6.5 at -110 odds. A 57.3% probability produces a 4.9% edge, making this a strong play for today's men's college basketball action.

Oregon +5.5 (-102)

• Edge: 4.7%
• Probability: 55.2%
• Matchup: Wisconsin vs. Oregon (11:00PM ET, Wednesday)

A 4.7% edge on a 55.2% probability makes Oregon +5.5 at -102 odds a solid value play in today's Wisconsin vs. Oregon matchup.

California +3.5 (-105)

• Edge: 4.6%
• Probability: 55.8%
• Matchup: SMU vs. California (10:00PM ET, Wednesday)

Our model projects value on California +3.5 at -105 odds. A 55.8% probability produces a 4.6% edge, making California the favorable side in Saturday’s matchup.

Texas ML (+285)

• Edge: 4.5%
• Probability: 30.5%
• Matchup: Seattle vs. Pepperdine (7:00PM ET, Wednesday)

Rounding out our top 10 bets, Texas to defeat Florida at +285 odds shows a 30.5% probability and a 4.5% edge.

NCAAM best bets summary: Wednesday, 2/25/2026

As of 6:05PM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Kansas State vs. Colorado	Colorado -6.5	-105 @ BetMGM	8.3%	59.5%
Xavier vs. Providence	Under 170.5 Points	-108 @ FanDuel	5.7%	57.6%
George Mason vs. Saint Joseph's (PA)	Over 135.5 Points	-110 @ BetMGM	5.7%	58.1%
Lehigh vs. American University	American University ML	-300 @ BetMGM	5.0%	80%
Nebraska-Omaha vs. South Dakota	Nebraska-Omaha +1.5	-125 @ BetMGM	5.0%	60.5%
Florida vs. Texas	Texas +7.5	-110 @ FanDuel	4.9%	57.3%
Seattle vs. Pepperdine	Seattle -6.5	-110 @ FanDuel	4.9%	57.3%
Wisconsin vs. Oregon	Oregon +5.5	-102 @ BetMGM	4.7%	55.2%
SMU vs. California	California +3.5	-105 @ FanDuel	4.6%	55.8%
Florida vs. Texas	Texas ML	+285 @ FanDuel	4.5%	30.5%

List of upcoming men's college basketball games to bet on now

• St. John's vs. Connecticut (7:00PM ET, Wednesday)
• Georgia vs. Vanderbilt (7:00PM ET, Wednesday)
• Florida vs. Texas (7:00PM ET, Wednesday)
• Maryland vs. Nebraska (7:00PM ET, Wednesday)
• Butler vs. Villanova (7:00PM ET, Wednesday)
• George Mason vs. Saint Joseph's (PA) (7:00PM ET, Wednesday)
• Illinois State vs. Northern Iowa (7:00PM ET, Wednesday)
• Davidson vs. Duquesne (7:00PM ET, Wednesday)
• North Texas vs. Charlotte (7:00PM ET, Wednesday)
• Wofford vs. East Tennessee State (7:00PM ET, Wednesday)

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Conclusion

Our men's college basketball best bets are locked and loaded for February 25, 2026, featuring plays such as Colorado -6.5 and under 170.5 points in the Xavier vs. Providence matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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