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March Madness picks today: Sunday's Second Round men's best bets highlight Iowa vs. Florida play [3/22/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get men's March Madness picks and NCAA Tournament best bets for Sunday, March 22, 2026.
Today’s men's March Madness picks for March 22, 2026 are here, with Iowa vs. Florida among the Second Round matchups identified as top value plays across Sunday’s NCAA Tournament play.
Dimers’ predictive analytics engine runs 24/7, going over the latest men's college basketball odds to uncover top betting edges throughout the bracket. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of men's March Madness picks today [3/22, updated 4:04PM ET]
Below, you’ll find today’s top men's March Madness bets, ranked by edge for Sunday, March 22, 2026.
Florida -10.5 (-102)
- Edge: 5.9%
- Probability: 56.4%
- Matchup: Iowa vs. Florida (7:10PM ET, Sunday)
Our model has identified value on Florida -10.5 at -102 odds. A 56.4% probability produces an edge of 5.9%, making this the strongest play for today's Second Round slate.
List of upcoming Men's March Madness games to bet on now
- St. John's vs. Kansas (5:15PM ET, Sunday)
- Tennessee vs. Virginia (6:10PM ET, Sunday)
- Iowa vs. Florida (7:10PM ET, Sunday)
- Utah State vs. Arizona (7:50PM ET, Sunday)
- UCLA vs. Connecticut (8:45PM ET, Sunday)
- Texas Tech vs. Alabama (9:45PM ET, Sunday)
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Make the most of our best bets today—including Florida -10.5—with the below offers:
Conclusion
Today's men's March Madness best bets are locked and loaded for March 22, 2026, featuring plays such as Florida -10.5. Powered by advanced simulations, these picks are here to boost your betting game.
All odds and probabilities in this article are correct and accurate at the time of publication.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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