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Dolphins vs. Panthers prediction: Why Miami is favored to win in NFL Week 5, 2025

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Written by Mac Douglass

Get Miami Dolphins vs Carolina Panthers predictions for NFL Sunday.

Miami Dolphins-Carolina Panthers Predictions and Game Preview.
Miami Dolphins vs. Carolina Panthers NFL prediction for Sunday, October 5, 2025.

The Carolina Panthers will take on the Miami Dolphins in NFL Week 5 action at Bank of America Stadium on Sunday, commencing at 1:00PM ET.

Based on updated simulations, Dimers' proven NFL model predicts the Dolphins as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Dolphins-Panthers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Dolphins with a win probability of 57%, while the Panthers have 43%."

This gameday Dolphins vs. Panthers betting preview builds on my Dolphins vs. Panthers prediction that was posted earlier in the week.

For a closer look at today’s game, including the predicted score, best bets and player prop picks, visit our interactive Dolphins vs. Panthers predictions page.

Dolphins vs. Panthers Predictions

Since our Dolphins-Panthers predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Dolphins and Panthers 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Dolphins a 57% chance of beating the Panthers in Week 5 of the NFL season. Our predicted final score has the Dolphins winning 22-20.

According to our model, the bookmakers have got it right, and the Dolphins and Panthers each have a 50% chance of covering the spread, while the 44.5-point over/under has a 56% chance of staying under.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 5 straight up picks.

Dolphins vs. Panthers odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Dolphins Panthers
Spread -1.5 (-104) +1.5 (-115)
Moneyline -118 +100
Total o44.5 (-104) u44.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Dolphins vs. Panthers picks and best bets

Our model's strongest edge in today's Dolphins vs. Panthers matchup is on the spread.

Our expert predictions, matched against the latest odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Dolphins vs. Panthers TD scorers

Who will score the first touchdown in Dolphins vs. Panthers?

According to our list of touchdown scorer predictions for Week 5, Miami's De'Von Achane is most likely to score the first TD in Dolphins vs. Panthers.

Our projections give Achane a 15.9% chance of getting in for six first at Bank of America Stadium, while the Dolphins running back is a 54.4% chance of reaching the end zone at any point in the game.

First touchdown scorer predictions

Miami Dolphins

Player First TD Probability
De'Von Achane (RB) 15.9%
Jaylen Waddle (WR) 8.3%
Ollie Gordon (RB) 5.5%

Carolina Panthers

Player First TD Probability
Rico Dowdle (RB) 10.1%
Tetairoa McMillan (WR) 8.5%
Trevor Etienne (RB) 4.7%

Anytime touchdown scorer predictions

Miami Dolphins

Player Anytime TD Probability
De'Von Achane (RB) 54.4%
Jaylen Waddle (WR) 33.5%
Ollie Gordon (RB) 23.8%

Carolina Panthers

Player Anytime TD Probability
Rico Dowdle (RB) 40.8%
Tetairoa McMillan (WR) 35.8%
Trevor Etienne (RB) 21.7%

Dolphins vs Panthers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Dolphins and Panthers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our NFL player projections page now to access player prop projections for every offensive player in this matchup and all other Week 5 games.

Dolphins vs. Panthers quarterbacks

Of the starting quarterbacks, the Dolphins' Tua Tagovailoa is projected to throw for more yards than the Panthers' Bryce Young.

Dolphins rushing

De'Von Achane, Ollie Gordon and Malik Washington are projected to be the leading rushers for the Dolphins.

Player Position
De'Von Achane RB
Ollie Gordon RB
Malik Washington WR

Panthers rushing

Rico Dowdle, Trevor Etienne and Bryce Young are expected to lead the Panthers in rushing yards.

Player Position
Rico Dowdle RB
Trevor Etienne RB
Bryce Young QB

Dolphins receiving

Jaylen Waddle, De'Von Achane, Malik Washington, Darren Waller and Nick Westbrook-Ikhine are projected to top the receiving yards for the Dolphins.

Player Position
Jaylen Waddle WR
De'Von Achane RB
Malik Washington WR
Darren Waller TE
Nick Westbrook-Ikhine WR

Panthers receiving

Tetairoa McMillan, Tommy Tremble, Xavier Legette, Hunter Renfrow and Brycen Tremayne are projected to lead the Panthers in receiving yards.

Player Position
Tetairoa McMillan WR
Tommy Tremble TE
Xavier Legette WR
Hunter Renfrow WR
Brycen Tremayne WR

Dolphins vs. Panthers game-day updates and essential details

The NFL Week 5 matchup between the Panthers and Dolphins at Bank of America Stadium is scheduled to start at 1:00PM ET.

Dimers' in-depth preview of Sunday's Dolphins vs. Panthers matchup includes our prediction, picks and the latest betting odds.

Before making any Dolphins vs. Panthers picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Dolphins, with a 57% win probability, will likely beat the Panthers in Week 5 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Dolphins vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Stay up-to-date with the latest NFL betting news and NFL parlay picks throughout the season. Plus, our Super Bowl odds offer the latest projections for the Super Bowl, AFC, NFC and each division.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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