Michigan State vs. Oregon prediction: Michigan State favored to win men's college basketball matchup [1/20/2026]

Oregon and Michigan State are scheduled to meet in men's college basketball action at Matthew Knight Arena on Tuesday, with tipoff at 9:00 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Michigan State as the most likely winner of the Michigan State vs. Oregon game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Michigan State vs. Oregon prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball game between Michigan State and Oregon 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Michigan State an 83% chance of beating Oregon. Our predicted final score has Michigan State winning 74-65.

According to our model, Oregon (+10.5) has a 54% chance of covering the spread, while the 137.5-point over/under has a 54% chance of going over.

Michigan State vs. Oregon odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Michigan State vs. Oregon picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: