Brewers vs. Cubs prediction: Why Cubs are favored to win Monday's MLB matchup [5/18/2026]

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Written by Dave Garofolo

Get Milwaukee Brewers vs Chicago Cubs predictions for MLB Monday.

Milwaukee Brewers-Chicago Cubs Predictions and Game Preview.
Milwaukee Brewers vs. Chicago Cubs MLB prediction for Monday, May 18, 2026.

The Chicago Cubs and Milwaukee Brewers will lock horns in MLB action at Wrigley Field on Monday, starting at 7:40 PM ET.

Shota Imanaga (4-3, 2.32 ERA) will get the ball for the Cubs, while the Brewers are going with Brandon Sproat (1-2, 5.75 ERA).

Based on the latest simulations, Dimers' advanced MLB model projects the Cubs as the most likely winner of the Brewers vs. Cubs game.

This article offers further insights into Monday's matchup, including best bets and picks.

Brewers vs. Cubs prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB game between the Brewers and Cubs, forming part of our MLB predictions coverage.

Our leading predictive model gives the Cubs a 58% chance of beating the Brewers.

According to our model, the Brewers (+1.5) have a 56% chance of covering the run line, while the over/under total of 10.5 runs has a 51% chance of staying under.

 

Brewers vs. Cubs odds [5/18/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Brewers Cubs
Run Line +1.5 (-130) -1.5 (+120)
Moneyline +136 -162
Total o10.5 (+100) u10.5 (-110)

All odds are correct at the time of publication and are subject to change.

Brewers vs. Cubs picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Brewers +1.5 -130
Moneyline Brewers +136
Total Under 10.5 -110

According to our best MLB bets, the top play to make on this game is Brewers +1.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Brewers vs. Cubs game-day updates and essential details

Monday's MLB action between the Cubs and Brewers at Wrigley Field is scheduled to begin at 7:40 PM ET.

Conclusion

We predict the Cubs, with a 58% win probability, will likely beat the Brewers in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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