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Brewers vs. Tigers prediction: Detroit favored to win Thursday's MLB matchup [4/23/2026]
Get Milwaukee Brewers vs Detroit Tigers predictions for MLB Thursday.

The Detroit Tigers will face the Milwaukee Brewers in MLB action at Comerica Park on Thursday, beginning at 1:10 PM ET.
Tarik Skubal (3-2, 2.08 ERA) will start on the mound for the Tigers, while the Brewers have opted for Brandon Sproat (0-1, 6.88 ERA).
Based on updated simulations, Dimers' advanced MLB model predicts the Tigers as the most likely winner of the Brewers vs. Tigers game.
This article offers further insights into Thursday's matchup, including best bets and picks.
Brewers vs. Tigers prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's MLB matchup between the Brewers and Tigers, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Tigers a 65% chance of defeating the Brewers.
According to our model, the Brewers (+1.5) have a 54% chance of covering the run line, while the over/under total of 6.5 runs has a 54% chance of going over.
Brewers vs. Tigers odds [4/23/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Brewers | Tigers |
|---|---|---|
| Run Line | +1.5 (-120) | -1.5 (+105) |
| Moneyline | +190 | -210 |
| Total | o6.5 (+101) | u6.5 (-131) |
All odds are correct at the time of publication and are subject to change.
Brewers vs. Tigers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Brewers +1.5 | -120 |
| Moneyline | Brewers | +190 |
| Total | Over 6.5 | +101 |
According to our MLB best bets, the top play to make on this game is Over 6.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Brewers vs. Tigers game-day updates and essential details
Thursday's MLB matchup between the Tigers and Brewers at Comerica Park is scheduled to start at 1:10 PM ET.
- Who: Milwaukee Brewers vs. Detroit Tigers
- Date: Thursday, April 23, 2026
- Time: 1:10 PM ET/10:10AM PT
- Venue: Comerica Park
Conclusion
We predict the Tigers, with a 65% win probability, will likely beat the Brewers in Thursday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
