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Mississippi Valley State vs. West Virginia prediction: Why West Virginia is favored to win men's college basketball matchup [12/22/2025]
Get Mississippi Valley State vs West Virginia predictions for college basketball Monday.

West Virginia will square off with Mississippi Valley State in men's college basketball action at Hope Coliseum on Monday, starting at 7:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model predicts West Virginia as the most likely winner of the Mississippi Valley State vs. West Virginia game.
This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.
Mississippi Valley State vs. West Virginia prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the outcome of Monday's NCAA basketball game between Mississippi Valley State and West Virginia 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives West Virginia a 100% chance of defeating Mississippi Valley State. Our predicted final score has West Virginia winning 84-52.
According to our model, Mississippi Valley State (+41.5) has a 60% chance of covering the spread, while the over/under total of 137.5 points has a 52% chance of staying under.
Mississippi Valley State vs. West Virginia odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Mississippi Valley State | West Virginia |
|---|---|---|
| Spread | +41.5 (-108) | -41.5 (-110) |
| Moneyline | +10000 | -100000 |
| Total | o137.5 (-108) | u137.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Mississippi Valley State vs. West Virginia picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Mississippi Valley State +41.5 | -108 |
| Moneyline | West Virginia | -100000 |
| Total | Under 137.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is Mississippi Valley State +41.5 at the spread.
Mississippi Valley State vs. West Virginia game-day updates and essential details
Monday's men's college basketball game between West Virginia and Mississippi Valley State at Hope Coliseum is scheduled to begin at 7:00 PM ET.
- Who: Mississippi Valley State vs. West Virginia
- Date: Monday, December 22, 2025
- Time: 7:00 PM ET/4:00PM PT
- Venue: Hope Coliseum
Conclusion
We predict West Virginia, with a 100% win probability, will likely beat Mississippi Valley State on Monday.
AI and automation have enhanced this article to quickly deliver accurate Mississippi Valley State vs. West Virginia insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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