Murray State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [2/18/2026]

Illinois State will take on Murray State in men's college basketball action at CEFCU Arena on Wednesday, commencing at 9:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Illinois State as the most likely winner of the Murray State vs. Illinois State game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Murray State vs. Illinois State prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Murray State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Illinois State a 60% chance of beating Murray State. Our predicted final score has Illinois State winning 78-75.

According to our model, Illinois State (-0.5) has a 55% chance of covering the spread, while the 158.5-point over/under has a 54% chance of staying under.

Murray State vs. Illinois State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Murray State vs. Illinois State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: