NFL picks straight up: Week 7, 2025

At Dimers.com, we offer NFL picks straight up for Week 7 and beyond, as part of our extensive NFL picks and NFL predictions coverage.

With Week 7 of the NFL season upon us, we've leveraged our state-of-the-art predictive analytics model to deliver a list of NFL straight up picks for all 15 games this week.

Get an edge in your NFL pick 'em contests by following our data-driven NFL Week 7 picks straight up, powered by thousands of game simulations.

Week 7 of the NFL season features 15 games, beginning with the Pittsburgh Steelers facing the Cincinnati Bengals on Thursday night and ending with the Houston Texans taking on the Seattle Seahawks on Monday.

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Full list of NFL Week 7 picks straight up

• Steelers (70% win probability)
• Rams (61%)
• Patriots (77%)
• Bears (67%)
• Browns (59%)
• Panthers (59%)
• Eagles (56%)
• Chiefs (85%)
• Broncos (77%)
• Chargers (55%)
• Commanders (57%)
• Packers (71%)
• 49ers (58%)
• Lions (68%)
• Seahawks (63%)

NFL picks this week straight up: Week 7, 2025

Listed below are our Week 7 NFL picks, highlighting how likely each team is to win their game this week.

Pittsburgh Steelers vs. Cincinnati Bengals

The Steelers kick off Week 7 against the Bengals at Paycor Stadium on Thursday night. According to our NFL model, the Steelers have a 70% chance of winning, while the Bengals have a 30% chance.

For Week 7's opening game, our model highlights NFL player props with Kenneth Gainwell (RB) as the most likely player from the Steelers to score the first TD at 9.9%, while Ja'Marr Chase (WR) is the top candidate from the Bengals at 9.5%.

The Pittsburgh Steelers vs. Cincinnati Bengals game at Paycor Stadium is scheduled for Thursday, October 16 at 8:15pm. All times stated in this article are in Eastern Standard Time (EST).

Los Angeles Rams vs. Jacksonville Jaguars

For this week's game between the Rams and the Jaguars, LA Rams is more likely to win. Our prediction model gives the Rams a 61% chance of winning. On the other hand, there is a 39% chance that the Jaguars will pull off an upset win.

The Los Angeles Rams vs. Jacksonville Jaguars matchup at Wembley Stadium will take place on Sunday, October 19 at 9:30am.

As the regular season approaches its conclusion, track the top teams with our updated NFL futures, highlighting top Super Bowl contenders.

New England Patriots vs. Tennessee Titans

We are picking the Patriots to win their game against the Titans this week, with our trusted NFL model projecting a 77% win probability for the road team. The Titans have a 23% chance of winning.

For betting purposes, the Titans are listed as +7 underdogs, with the Patriots' moneyline at -325.

The New England Patriots vs. Tennessee Titans game at Nissan Stadium is slated for Sunday, October 19 at 1:00pm.

New Orleans Saints vs. Chicago Bears

According to our predictive analytics model, the Bears are the team to beat in this game, with their win probability at 67%. The Saints, on the other hand, have a 33% chance of winning.

The New Orleans Saints vs. Chicago Bears game at Soldier Field is set for Sunday, October 19 at 1:00pm.

Miami Dolphins vs. Cleveland Browns

The Browns have a 59% chance of winning on Sunday afternoon, compared to the Dolphins' 41% chance of victory. This makes the Cleveland Browns our pick to win at Huntington Bank Field.

The Miami Dolphins vs. Cleveland Browns matchup at Huntington Bank Field is scheduled for Sunday, October 19 at 1:00pm.

Carolina Panthers vs. New York Jets

The Panthers are favorites to win here, with our model giving them a 59% chance, while the Jets enter the weekend with a 41% chance of securing a win at MetLife Stadium.

When it comes to betting on this game, the Panthers' moneyline odds are set at -130, with the home team Jets listed as +1.5 underdogs.

The Carolina Panthers vs. New York Jets game at MetLife Stadium will take place on Sunday, October 19 at 1:00pm.

Philadelphia Eagles vs. Minnesota Vikings

After 10,000 simulations of Eagles vs. Vikings this Sunday, our model projects the Eagles as the more likely winners with a probability of 56%. Their opponents, the Vikings, have a 44% chance of getting the win at home.

The Philadelphia Eagles vs. Minnesota Vikings matchup at U.S. Bank Stadium is slated for Sunday, October 19 at 1:00pm.

Las Vegas Raiders vs. Kansas City Chiefs

We are picking the Chiefs, who have an 85% chance of winning the matchup, while the Raiders have a 15% win probability.

The Las Vegas Raiders vs. Kansas City Chiefs game at GEHA Field at Arrowhead Stadium will take place on Sunday, October 19 at 1:00pm.

New York Giants vs. Denver Broncos

The next game of Week 7 sees the Giants take on the Broncos at Empower Field at Mile High.

We predict the Broncos to win with a probability of 77%, while the Giants are projected to have a win chance of 23%.

As for the Vegas betting odds here, the Broncos are listed as -7 favorites, with the Giants' moneyline odds posted at +285.

The New York Giants vs. Denver Broncos game at Empower Field at Mile High is scheduled for Sunday, October 19 at 4:05pm.

Indianapolis Colts vs. Los Angeles Chargers

The likely winner of this matchup is the Chargers, who have a projected win chance of 55%, according to DimersBOT. On the other side of this matchup, the Colts have a projected win probability of 45%.

The Indianapolis Colts vs. Los Angeles Chargers matchup at SoFi Stadium is set for Sunday, October 19 at 4:05pm.

Washington Commanders vs. Dallas Cowboys

We have run our powerful NFL model over this week’s Commanders-Cowboys clash 10,000 times, with the Commanders coming out as the team to pick. Of those 10,000 simulations, the Commanders won 5,712 times, with the Cowboys winning on 4,288 occasions.

The Washington Commanders vs. Dallas Cowboys game at AT&T Stadium is scheduled for Sunday, October 19 at 4:25pm.

Green Bay Packers vs. Arizona Cardinals

Next up is the game between the Packers and Cardinals, with our model projecting the road team as the more likely victor, with the Packers rated as having a 71% chance of getting the W. The Cardinals, on the other hand, are projected to have a 29% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Packers' moneyline odds set at -300 for this road game, while the hosting Cardinals are listed as +6.5 underdogs.

The Green Bay Packers vs. Arizona Cardinals game at State Farm Stadium will take place on Sunday, October 19 at 4:25pm.

Atlanta Falcons vs. San Francisco 49ers

Our next straight up pick this week is for the 49ers to get the win against the Falcons. After running 10,000 simulations of this matchup, the San Francisco have a win probability of 58%, with the Falcons at 42%.

The Atlanta Falcons vs. San Francisco 49ers game at Levi's Stadium is slated for Sunday, October 19 at 8:20pm.

Tampa Bay Buccaneers vs. Detroit Lions

With a win probability of 68% on Monday night, our straight up pick for this game is the Lions, while their opponent, the Buccaneers, have a projected win chance of 32%.

The Tampa Bay Buccaneers vs. Detroit Lions game at Ford Field will take place on Monday, October 20 at 7:00pm.

For a different angle on this week's NFL action, explore Dimers' NFL trends to find the latest player prop trends.

Houston Texans vs. Seattle Seahawks

The team to pick here is the Seahawks, who have a 63% chance of winning their matchup against the Texans this Sunday night.

Looking at the betting odds for this Monday Night Football clash, the Seahawks are listed as -3.5 favorites at home, with the Texans' moneyline odds available at +150.

The Houston Texans vs. Seattle Seahawks game at Lumen Field is scheduled for Monday, October 20 at 10:00pm.

For more insights into this week's NFL predictions, check out the latest from the Dimers Sports Betting Podcast:

NFL straight up picks and predictions for Week 7

The NFL Week 7 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

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Please note that all NFL odds and probabilities mentioned on this page are subject to change.