...
...
Read Article
Ohio State vs. Northwestern prediction: Northwestern favored to win men's college basketball matchup [12/6/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Ohio State vs Northwestern predictions for college basketball Saturday.
Northwestern will take on Ohio State in men's college basketball action at Welsh-Ryan Arena on Saturday, beginning at 2:00PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Northwestern as the most likely winner of the Ohio State vs. Northwestern game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Ohio State vs. Northwestern prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball matchup between Ohio State and Northwestern 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Northwestern a 56% chance of beating Ohio State. Our predicted final score has Northwestern winning 76-74.
According to our model, Northwestern (+1.5) has a 58% chance of covering the spread, while the over/under total of 155.5 points has a 55% chance of staying under.
Ohio State vs. Northwestern odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Ohio State | Northwestern |
|---|---|---|
| Spread | -1.5 (+105) | +1.5 (-122) |
| Moneyline | -105 | -102 |
| Total | o155.5 (-108) | u155.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Ohio State vs. Northwestern picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Northwestern +1.5 | -122 |
| Moneyline | Northwestern | -102 |
| Total | Under 155.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Northwestern to win.
Ohio State vs. Northwestern game-day updates and essential details
Saturday's men's college basketball matchup between Northwestern and Ohio State at Welsh-Ryan Arena is scheduled to begin at 2:00PM ET.
- Who: Ohio State vs. Northwestern
- Date: Saturday, December 6, 2025
- Time: 2:00PM ET/11:00AM PT
- Venue: Welsh-Ryan Arena
Sports betting deals available for Missouri sports betting launch
To truly take advantage of the recent Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that grants you the best opening offer in the game. Don't miss out!
Conclusion
We predict Northwestern, with a 56% win probability, will likely beat Ohio State on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Northwestern insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
Advertiser disclosure