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Penn State vs. Indiana prediction: Why Indiana is favored to win men's college basketball matchup [12/9/2025]
Get Penn State vs Indiana predictions for college basketball Tuesday.

Men's college basketball action continues on Tuesday at 8:30PM ET as Penn State squares off with Indiana in men's college basketball action at Simon Skjodt Assembly Hall.
Based on the latest simulations, Dimers' advanced college basketball model projects Indiana as the most likely winner of the Penn State vs. Indiana game.
This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Penn State vs. Indiana prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball game between Penn State and Indiana 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Indiana a 91% chance of beating Penn State. Our predicted final score has Indiana winning 83-68.
According to our model, Indiana (-14.5) has a 53% chance of covering the spread, while the over/under total of 152.5 points has an equal 50-50 chance of hitting.
Penn State vs. Indiana odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Penn State | Indiana |
|---|---|---|
| Spread | +14.5 (-110) | -14.5 (-105) |
| Moneyline | +800 | -1350 |
| Total | o152.5 (-105) | u152.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Penn State vs. Indiana picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Indiana -14.5 | -105 |
| Moneyline | Penn State | +800 |
| Total | Over 152.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Indiana -14.5 at the spread.
Penn State vs. Indiana game-day updates and essential details
Tuesday's men's college basketball matchup between Indiana and Penn State at Simon Skjodt Assembly Hall is scheduled to start at 8:30PM ET.
- Who: Penn State vs. Indiana
- Date: Tuesday, December 9, 2025
- Time: 8:30PM ET/5:30PM PT
- Venue: Simon Skjodt Assembly Hall
Conclusion
We predict Indiana, with a 91% win probability, will likely beat Penn State on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Penn State vs. Indiana insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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