Purdue vs. Arizona prediction: Why Arizona is favored to win men's March Madness Elite Eight matchup [3/28/2026]

Arizona and Purdue will lock horns in March Madness Elite Eight action at SAP Center at San Jose on Saturday, with tipoff at 8:49 PM ET.

For this NCAA Tournament game, Arizona—a complete team with a monstrous frontcourt and NBA-level talent— take on Purdue, a veteran group led by the winningest senior class in school history.

Based on the latest simulation results, Dimers' proven college basketball model projects Arizona as the most likely winner of the Purdue vs. Arizona game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Purdue vs. Arizona prediction: Who will win and advance to the Final Four?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAAM Tournament game between Purdue and Arizona, forming part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Arizona a 73% chance of beating Purdue. Our predicted final score has Arizona winning 80-73.

According to our model, Arizona (-5.5) has a 55% chance of covering the spread, while the over/under total of 153.5 points has a 53% chance of going over.

Purdue vs. Arizona odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Purdue vs. Arizona picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: