San Francisco 49ers vs. Seattle Seahawks: Experts release early Divisional Round predictions [2026]

The San Francisco 49ers and Seattle Seahawks will meet in the Divisional Round at Lumen Field on Saturday, January 17, 2026, starting at 8:00 PM ET.

Early simulations from Dimers' trusted NFL model favor the Seahawks as the most likely winner of this NFC West rivalry clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive 49ers vs. Seahawks predictions page.

San Francisco vs. Seattle early predictions

Leveraging trusted machine learning and analysis, we have simulated the Niners vs. Seahawks game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: 49ers 25%, Seahawks 75%
• Predicted final score: 49ers 19-25 Seahawks
• Spread: 49ers (+7.5) 56%, Seahawks (-7.5) 44%
• Total points (45.5): Over 45%, Under 55%

As of January 13, 2026, these 49ers-Seahawks calculations and predictions reflect the latest data and insights available.

Niners vs. Seahawks Divisional Round details

Saturday's action between the Seahawks and 49ers at Lumen Field is scheduled for January 17, 2026.

• Who: San Francisco 49ers vs. Seattle Seahawks
• Date: Saturday, January 17, 2026
• Time: 8:00 PM ET/5:00PM PT
• Venue: Lumen Field

Niners vs. Seahawks opening odds

We've researched the best betting odds across America for this Divisional Round clash, which are listed here:

• Spread: 49ers +7.5 (-110), Seahawks -7.5 (-108)
• Moneyline: 49ers +310, Seahawks -355
• Total: Over/Under 45.5 (-108/-105)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for the Divisional Round highlight the top candidates to score a TD in Niners-Seahawks in Week 20:

San Francisco 49ers

• Christian McCaffrey: 66.5% probability
• Jauan Jennings: 39.9% probability
• Jake Tonges: 30.9% probability

Seattle Seahawks

• Zach Charbonnet: 45.2% probability
• Jaxon Smith-Njigba: 44.5% probability
• Kenneth Walker: 36.6% probability

49ers vs Seahawks player props

Christian McCaffrey is projected to lead rushing for the 49ers, while Kenneth Walker is expected to pace the Seahawks on the ground.

In the receiving game, our projections favor San Francisco's Jauan Jennings and Seattle's Jaxon Smith-Njigba as the likely leaders for each team.

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Conclusion

We predict the Seahawks, with a 75% win probability, will likely beat the 49ers in this NFL postseason matchup. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the 49ers vs. Seahawks game, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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