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49ers vs. Seahawks prediction: Seattle favored to win Divisional Round game [2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get San Francisco 49ers vs Seattle Seahawks predictions for NFL Saturday.
The Seattle Seahawks will square off with the San Francisco 49ers in the Divisional Round of the NFL Playoffs at Lumen Field on Saturday, starting at 8:00 PM ET.
Based on updated simulations, Dimers' advanced NFL model projects the Seahawks as the most likely winner of the 49ers vs. Seahawks game.
This article offers further insights into Saturday's matchup, including projected touchdown scorers, best bets and player prop picks.
Niners vs. Seahawks prediction: Who will win and cover?
Since our 49ers-Seahawks predictions earlier in the week, we have simulated the outcome of Saturday's NFL matchup between the 49ers and Seahawks 10,000 times as part of our NFL predictions coverage.
Our famous predictive model gives the Seahawks a 73% chance of defeating the 49ers. Our predicted final score has the Seahawks winning 25-19.
According to our model, the 49ers (+7) have a 53% chance of covering the spread, while the over/under total of 44 points has a 52% chance of going over.
To see win probabilities for every matchup this week, check out our expert NFL Week 20 straight up picks.
49ers vs. Seahawks odds
We have researched the best NFL odds in America for this game, which are listed here:
| Bet Type | 49ers | Seahawks |
|---|---|---|
| Spread | +7 (+100) | -7 (-108) |
| Moneyline | +250 | -295 |
| Total | o44 (-110) | u44 (-110) |
All odds are correct at the time of publication and are subject to change.
49ers vs. Seahawks picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | 49ers +7 | +100 |
| Moneyline | Seahawks | -295 |
| Total | Over 44 | -110 |
According to our NFL best bets, the top play to make on this game is 49ers +7 at the spread.
49ers vs. Seahawks TD scorers
Who will score a touchdown in 49ers vs. Seahawks?
According to our list of touchdown scorer predictions for today, Christian McCaffrey is most likely to score an anytime touchdown in 49ers vs. Seahawks.
Our projections give McCaffrey a 57.0% chance of getting in for six at Lumen Field, while the running back is a 14.3% chance of scoring the first touchdown the game.
Anytime touchdown scorer predictions
San Francisco 49ers
| Player | Anytime TD Probability |
|---|---|
| Christian McCaffrey (RB) | 57.0% |
| Jauan Jennings (WR) | 29.8% |
| Jake Tonges (TE) | 25.3% |
| Demarcus Robinson (WR) | 18.3% |
| Ricky Pearsall (WR) | 18.0% |
Seattle Seahawks
| Player | Anytime TD Probability |
|---|---|
| Zach Charbonnet (RB) | 46.8% |
| Jaxon Smith-Njigba (WR) | 45.0% |
| Kenneth Walker (RB) | 38.2% |
| AJ Barner (TE) | 32.3% |
| Rashid Shaheed (WR) | 22.1% |
First touchdown scorer predictions
San Francisco 49ers
| Player | First TD Probability |
|---|---|
| Christian McCaffrey (RB) | 14.3% |
| Jauan Jennings (WR) | 6.0% |
| Jake Tonges (TE) | 4.9% |
| Demarcus Robinson (WR) | 3.4% |
| Ricky Pearsall (WR) | 3.4% |
Seattle Seahawks
| Player | First TD Probability |
|---|---|
| Zach Charbonnet (RB) | 12.0% |
| Jaxon Smith-Njigba (WR) | 11.4% |
| Kenneth Walker (RB) | 9.1% |
| AJ Barner (TE) | 7.4% |
| Rashid Shaheed (WR) | 4.7% |
49ers vs Seahawks player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the 49ers and Seahawks. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 20 games.
Quarterbacks
Of the starting quarterbacks, the 49ers' Brock Purdy is projected for 235 passing yards. The Seahawks' Sam Darnold is expected to throw for 218 yards.
| Player | Proj. Pass Yards |
|---|---|
| Brock Purdy (SF) | 235 |
| Sam Darnold (SEA) | 218 |
49ers rushing
| Player | Proj. Rush Yards |
|---|---|
| Christian McCaffrey | 62 |
| Brock Purdy | 22 |
| Brian Robinson | 14 |
Seahawks rushing
| Player | Proj. Rush Yards |
|---|---|
| Kenneth Walker | 60 |
| Zach Charbonnet | 49 |
| Sam Darnold | 8 |
49ers receiving
| Player | Proj. Rec. Yards |
|---|---|
| Christian McCaffrey | 52 |
| Jauan Jennings | 45 |
| Jake Tonges | 39 |
| Ricky Pearsall | 32 |
| Demarcus Robinson | 30 |
Seahawks receiving
| Player | Proj. Rec. Yards |
|---|---|
| Jaxon Smith-Njigba | 95 |
| Cooper Kupp | 36 |
| AJ Barner | 31 |
| Rashid Shaheed | 30 |
| Kenneth Walker | 17 |
Niners vs. Seahawks game-day updates and essential details
Saturday's action between the Seahawks and 49ers at Lumen Field is scheduled to start at 8:00 PM ET.
- Who: San Francisco 49ers vs. Seattle Seahawks
- Date: Saturday, January 17, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Lumen Field
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Conclusion
We predict the Seahawks, with a 73% win probability, will likely beat the 49ers on Saturday.
AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Seahawks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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