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San Francisco 49ers vs. Seattle Seahawks updated prediction featuring Christian McCaffrey, Zach Charbonnet [Divisional Round, 2026]

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Written by Jason Bevilacqua

Get new expert 49ers vs Seahawks predictions for Saturday's game.

San Francisco 49ers-Seattle Seahawks Latest Predictions and Betting Preview.
Predictions for the San Francisco 49ers and Seattle Seahawks matchup at Lumen Field this Saturday.

Dimers' latest NFL predictions are live for Seattle Seahawks vs. San Francisco 49ers in Divisional Round of the playoffs, with our model giving the Seahawks a 74% of winning.

As Saturday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this NFC West clash.

Since our early Seahawks-49ers predictions, we’ve updated the win probabilities, score projections, and TD odds for Christian McCaffrey, Zach Charbonnet, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our 49ers vs. Seahawks page.

What's changed? San Francisco vs. Seattle updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Niners vs. Seahawks matchup stacks up. Here are the updated forecasts:

  • Straight Up Win Probabilities: 49ers 26%, Seahawks 74%
  • Predicted Final Score: 49ers 19-25 Seahawks
  • Spread: 49ers (+7) 50%, Seahawks (-7) 50%
  • Total Points (44.5): Over 53%, Under 47%

As of January 15, 2026, these 49ers-Seahawks figures reflect changes since our early-week simulation.

 

Anytime touchdown scorer predictions

New NFL player projections for the Divisional Round highlight the top candidates to find the end zone in Niners-Seahawks on Saturday:

San Francisco 49ers

  • Christian McCaffrey: 56.7% probability
  • Jauan Jennings: 31.5% probability
  • Jake Tonges: 24.6% probability

Seattle Seahawks

  • Zach Charbonnet: 48.1% probability
  • Jaxon Smith-Njigba: 45.2% probability
  • Kenneth Walker: 38.2% probability

Niners vs. Seahawks latest odds

The best current odds from the top sportsbooks in the US:

  • Spread: 49ers +7 (-102), Seahawks -7 (-115)
  • Moneyline: 49ers +280, Seahawks -345
  • Total: Over/Under 44.5 (-118/-104)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Niners vs. Seahawks Divisional Round details

Saturday's game between the Seahawks and 49ers at Lumen Field is scheduled for January 17, 2026.

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Conclusion

We predict the Seahawks, with a 74% win probability, will likely beat the 49ers in this NFL postseason matchup. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the 49ers vs. Seahawks matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on NFL

Stay up-to-date with the latest NFL news and data-driven parlay picks all season long. Plus, our Super Bowl odds for top predictions and the best available odds on the Super Bowl, AFC, NFC and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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