Seattle Seahawks vs. Jacksonville Jaguars early prediction: Expert picks for NFL Week 6, 2025

The Seattle Seahawks and Jacksonville Jaguars will meet in Week 6 of the NFL season at EverBank Stadium on Sunday, October 12, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Jaguars as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Seahawks vs. Jaguars predictions page.

Seattle vs. Jacksonville early predictions

Leveraging trusted machine learning and analysis, we have simulated the Seahawks vs. Jaguars game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Seahawks 46%, Jaguars 54%
• Predicted final score: Seahawks 22-23 Jaguars
• Spread: Seahawks (+1.5) 50%, Jaguars (-1.5) 50%
• Total points (46.5): Over 47%, Under 53%

As of October 5, 2025, these Seahawks-Jaguars figures and predictions reflect the latest data and insights available.

Seahawks vs. Jaguars Week 6 details

The NFL Week 6 matchup between the Jaguars and Seahawks at EverBank Stadium is scheduled for October 12, 2025.

• Who: Seattle Seahawks vs. Jacksonville Jaguars
• Date: Sunday, October 12, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: EverBank Stadium

Seahawks vs. Jaguars opening odds

We've researched the best betting odds across America for this Week 6 game, which are listed here:

• Spread: Seahawks +1.5 (-110), Jaguars -1.5 (-110)
• Moneyline: Seahawks +105, Jaguars -125
• Total: Over/Under 46.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Jaguars, with a 54% win probability, will likely beat the Seahawks in Week 6 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Seahawks vs. Jaguars matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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