Seattle Seahawks vs. San Francisco 49ers updated prediction featuring Jaxon Smith-Njigba, Christian McCaffrey [Week 18, 2026]

Dimers' latest NFL predictions are live for San Francisco 49ers vs. Seattle Seahawks in Week 18, with our model giving the Seahawks a 56% of winning.

As Saturday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this NFC West clash.

Since our early 49ers-Seahawks predictions, we’ve updated the win probabilities, score projections, and TD odds for Jaxon Smith-Njigba, Christian McCaffrey, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—head to our Seahawks vs. 49ers page.

What's changed? Seattle vs. San Francisco updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Seahawks vs. Niners matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Seahawks 56%, 49ers 44%
• Predicted Final Score: Seahawks 24-22 49ers
• Spread: Seahawks (-1.5) 50%, 49ers (+1.5) 50%
• Total Points (48): Over 45%, Under 55%

As of January 1, 2026, these Seahawks-49ers calculations reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 18 highlight the top candidates to find the end zone in Seahawks-Niners on Saturday:

Seattle Seahawks

• Jaxon Smith-Njigba: 47.8% probability
• Zach Charbonnet: 42.3% probability
• Kenneth Walker: 36.1% probability

San Francisco 49ers

• Christian McCaffrey: 60.4% probability
• George Kittle: 36.6% probability
• Jauan Jennings: 33.6% probability

Seahawks vs. Niners latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Seahawks -1.5 (-108), 49ers +1.5 (-108)
• Moneyline: Seahawks -118, 49ers +100
• Total: Over/Under 48 (-118/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Seahawks vs. Niners Week 18 details

The NFL Week 18 action between the 49ers and Seahawks at Levi's Stadium is scheduled for January 3, 2026.

• Who: Seattle Seahawks vs. San Francisco 49ers
• Date: Saturday, January 3, 2026
• Time: 8:00 PM ET/5:00PM PT
• Venue: Levi's Stadium

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Conclusion

We predict the Seahawks, with a 56% win probability, will likely beat the 49ers in Week 18 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Seahawks vs. 49ers game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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