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SIUE vs. Western Illinois prediction: Why SIU-Edwardsville is favored to win men's college basketball matchup [12/22/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get SIUE vs Western Illinois predictions for college basketball Monday.
Men's college basketball action continues on Monday at 4:30 PM ET as the favored SIUE takes on Western Illinois in men's college basketball action at LeRoy A. Ufkes Court at Western Hall.
Based on updated simulation results, Dimers' proven college basketball model predicts SIU-Edwardsville as the most likely winner of the SIUE vs. Western Illinois game.
This article offers an expanded analysis of Monday's matchup, including an expanded look at the predicted score, best bets and picks.
SIUE vs. Western Illinois prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the outcome of Monday's NCAA basketball matchup between SIUE and Western Illinois 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives SIU-Edwardsville a 74% chance of beating Western Illinois. Our predicted final score has SIU-Edwardsville winning 72-66.
According to our model, the bookies have got it right, and SIU-Edwardsville and Western Illinois each have a 50% chance of covering the spread, while the over/under total of 138.5 points has a 52% chance of staying under.
SIUE vs. Western Illinois odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | SIUE | Western Illinois |
|---|---|---|
| Spread | -6.5 (-106) | +6.5 (-105) |
| Moneyline | -278 | +230 |
| Total | o138.5 (-108) | u138.5 (-110) |
All odds are correct at the time of publication and are subject to change.
SIUE vs. Western Illinois picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Western Illinois +6.5 | -105 |
| Moneyline | SIU-Edwardsville | -278 |
| Total | Under 138.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is SIU-Edwardsville to win.
SIUE vs. Western Illinois game-day updates and essential details
Monday's men's college basketball action between Western Illinois and SIUE at LeRoy A. Ufkes Court at Western Hall is scheduled to begin at 4:30 PM ET.
- Who: SIU-Edwardsville vs. Western Illinois
- Date: Monday, December 22, 2025
- Time: 4:30 PM ET/1:30PM PT
- Venue: LeRoy A. Ufkes Court at Western Hall
Conclusion
We predict SIU-Edwardsville, with a 74% win probability, will likely beat Western Illinois on Monday.
AI and automation have enhanced this article to quickly deliver accurate SIU-Edwardsville vs. Western Illinois insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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