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South Carolina State vs. Samford prediction: Samford favored to win men's college basketball matchup [11/7/2025]

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Written by Mac Douglass

Get South Carolina State vs Samford predictions for college basketball Friday.

South Carolina State-Samford Predictions and Game Preview.
South Carolina State vs. Samford men's college basketball prediction for Friday, November 7, 2025.

Samford will take on South Carolina State in men's college basketball action at Pete Hanna Center on Friday, starting at 8:30PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Samford as the most likely winner of the South Carolina State vs. Samford game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

South Carolina State vs. Samford prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Friday's NCAA basketball matchup between South Carolina State and Samford 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Samford a 90% chance of beating South Carolina State. Our predicted final score has Samford winning 85-70.

According to our model, Samford (-14.5) has a 53% chance of covering the spread, while the over/under total of 155.5 points has a 52% chance of going over.

 

South Carolina State vs. Samford odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type South Carolina State Samford
Spread +14.5 (-110) -14.5 (-110)
Moneyline +820 -1200
Total o155.5 (-112) u155.5 (-108)

All odds are correct at the time of publication and are subject to change.

South Carolina State vs. Samford picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Samford -14.5 -110
Moneyline South Carolina State +820
Total Over 155.5 -112

According to our men's college basketball best bets, the top play to make on this game is Samford -14.5 at the spread.

 

South Carolina State vs. Samford game-day updates and essential details

Friday's men's college basketball game between Samford and South Carolina State at Pete Hanna Center is scheduled to start at 8:30PM ET.

  • Who: South Carolina State vs. Samford
  • Date: Friday, November 7, 2025
  • Time: 8:30PM ET/5:30PM PT
  • Venue: Pete Hanna Center

Conclusion

We predict Samford, with a 90% win probability, will likely beat South Carolina State on Friday.

AI and automation have enhanced this article to quickly deliver accurate South Carolina State vs. Samford insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on men's college basketball

Keep up with the latest men's college basketball news and CBB parlay picks throughout the season. Plus, our NCAA Tournament Championship odds offer the most up-to-date probabilities for every March Madness contender.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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