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St. Bonaventure vs. Buffalo prediction: St. Bonaventure favored to win men's college basketball matchup [12/6/2025]

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Written by Dave Garofolo

Get St. Bonaventure vs Buffalo predictions for college basketball Saturday.

St. Bonaventure-Buffalo Predictions and Game Preview.
St. Bonaventure vs. Buffalo men's college basketball prediction for Saturday, December 6, 2025.

Buffalo will take on the favored St. Bonaventure in men's college basketball action at Alumni Arena on Saturday, starting at 2:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts St. Bonaventure as the most likely winner of the St. Bonaventure vs. Buffalo game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

St. Bonaventure vs. Buffalo prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball game between St. Bonaventure and Buffalo 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives St. Bonaventure a 68% chance of defeating Buffalo. Our predicted final score has St. Bonaventure winning 74-69.

According to our model, Buffalo (+5.5) has a 55% chance of covering the spread, while the over/under total of 144.5 points has an equal 50-50 chance of hitting.

 

St. Bonaventure vs. Buffalo odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type St. Bonaventure Buffalo
Spread -5.5 (-112) +5.5 (-105)
Moneyline -250 +215
Total o144.5 (-105) u144.5 (-110)

All odds are correct at the time of publication and are subject to change.

St. Bonaventure vs. Buffalo picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Buffalo +5.5 -105
Moneyline Buffalo +215
Total Over 144.5 -105

According to our men's college basketball best bets, the top play to make on this game is Buffalo +5.5 at the spread.

 

St. Bonaventure vs. Buffalo game-day updates and essential details

Saturday's men's college basketball action between Buffalo and St. Bonaventure at Alumni Arena is scheduled to begin at 2:00PM ET.

  • Who: St. Bonaventure vs. Buffalo
  • Date: Saturday, December 6, 2025
  • Time: 2:00PM ET/11:00AM PT
  • Venue: Alumni Arena

 

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Conclusion

We predict St. Bonaventure, with a 68% win probability, will likely beat Buffalo on Saturday.

AI and automation have enhanced this article to quickly deliver accurate St. Bonaventure vs. Buffalo insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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