USC Upstate vs. Winthrop prediction: Why Winthrop is favored to win men's college basketball matchup [2/19/2026]

Winthrop will square off with USC Upstate in men's college basketball action at Winthrop Coliseum on Thursday, commencing at 6:30 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Winthrop as the most likely winner of the USC Upstate vs. Winthrop game.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

USC Upstate vs. Winthrop prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Thursday's NCAA basketball matchup between USC Upstate and Winthrop 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Winthrop an 88% chance of defeating USC Upstate. Our predicted final score has Winthrop winning 86-72.

According to our model, the bookmakers have got it right, and USC Upstate and Winthrop each have a 50% chance of covering the spread, while the 155.5-point over/under has a 53% chance of going over.

USC Upstate vs. Winthrop odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

USC Upstate vs. Winthrop picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: