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USC vs. San Diego prediction: USC favored to win men's college basketball matchup [12/9/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get USC vs San Diego predictions for college basketball Tuesday.
Men's college basketball action continues on Tuesday at 9:00PM ET as the favored USC locks horns with San Diego in men's college basketball action at Jenny Craig Pavilion.
Based on the latest simulations, Dimers' proven college basketball model projects USC as the most likely winner of the USC vs. San Diego game.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
USC vs. San Diego prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the result of Tuesday's NCAA basketball matchup between USC and San Diego 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives USC a 90% chance of beating San Diego. Our predicted final score has USC winning 84-69.
According to our model, San Diego (+15.5) has a 53% chance of covering the spread, while the over/under total of 158.5 points has a 55% chance of staying under.
USC vs. San Diego odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | USC | San Diego |
|---|---|---|
| Spread | -15.5 (-110) | +15.5 (-110) |
| Moneyline | -1600 | +1000 |
| Total | o158.5 (-108) | u158.5 (-105) |
All odds are correct at the time of publication and are subject to change.
USC vs. San Diego picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | San Diego +15.5 | -110 |
| Moneyline | San Diego | +1000 |
| Total | Under 158.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 158.5 total points.
USC vs. San Diego game-day updates and essential details
Tuesday's men's college basketball matchup between San Diego and USC at Jenny Craig Pavilion is scheduled to begin at 9:00PM ET.
- Who: USC vs. San Diego
- Date: Tuesday, December 9, 2025
- Time: 9:00PM ET/6:00PM PT
- Venue: Jenny Craig Pavilion
Conclusion
We predict USC, with a 90% win probability, will likely beat San Diego on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate USC vs. San Diego insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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