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Vanderbilt vs. Memphis prediction: Why Vanderbilt is favored to win men's college basketball matchup [12/17/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Vanderbilt vs Memphis predictions for college basketball Wednesday.
Memphis will face the favored Vanderbilt in men's college basketball action at FedExForum on Wednesday, beginning at 7:00 PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model predicts Vanderbilt as the most likely winner of the Vanderbilt vs. Memphis game.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Vanderbilt vs. Memphis prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Vanderbilt and Memphis 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Vanderbilt a 76% chance of defeating Memphis. Our predicted final score has Vanderbilt winning 83-75.
According to our model, Memphis (+9.5) has a 57% chance of covering the spread, while the 159.5-point over/under has a 51% chance of staying under.
Vanderbilt vs. Memphis odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Vanderbilt | Memphis |
|---|---|---|
| Spread | -9.5 (-105) | +9.5 (-110) |
| Moneyline | -450 | +400 |
| Total | o159.5 (-115) | u159.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Vanderbilt vs. Memphis picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Memphis +9.5 | -110 |
| Moneyline | Memphis | +400 |
| Total | Under 159.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Memphis +9.5 at the spread.
Vanderbilt vs. Memphis game-day updates and essential details
Wednesday's men's college basketball matchup between Memphis and Vanderbilt at FedExForum is scheduled to start at 7:00 PM ET.
- Who: Vanderbilt vs. Memphis
- Date: Wednesday, December 17, 2025
- Time: 7:00 PM ET/4:00PM PT
- Venue: FedExForum
Conclusion
We predict Vanderbilt, with a 76% win probability, will likely beat Memphis on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Vanderbilt vs. Memphis insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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