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Nationals vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [3/29/2026]

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Written by Dave Garofolo

Get Washington Nationals vs Chicago Cubs predictions for MLB Sunday.

Washington Nationals-Chicago Cubs Predictions and Game Preview.
Washington Nationals vs. Chicago Cubs MLB prediction for Sunday, March 29, 2026.

The Chicago Cubs will square off with the Washington Nationals in MLB action at Wrigley Field on Sunday, commencing at 2:20 PM ET.

The Cubs will start Shota Imanaga (0-0, 0.00 ERA), while the Nationals have opted for Jake Irvin (0-0, 0.00 ERA).

Based on the latest simulation results, Dimers' new and improved MLB model predicts the Cubs as the most likely winner of the Nationals vs. Cubs game.

This article offers an expanded analysis of Sunday's matchup, including best bets and picks.

Nationals vs. Cubs prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Sunday's MLB matchup between the Nationals and Cubs, forming part of our MLB predictions coverage.

Our independent predictive model currently gives the Cubs a 68% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 51% chance of covering the run line, while the 9.5-run over/under has a 55% chance of staying under.

 

Nationals vs. Cubs odds [3/29/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Nationals Cubs
Run Line +1.5 (+105) -1.5 (-118)
Moneyline +210 -248
Total o9.5 (+100) u9.5 (-122)

All odds are correct at the time of publication and are subject to change.

Nationals vs. Cubs picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Nationals +1.5 +105
Moneyline Nationals +210
Total Under 9.5 -122

According to our MLB best bets, the top play to make on this game is Nationals +1.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Nationals vs. Cubs game-day updates and essential details

Sunday's MLB matchup between the Cubs and Nationals at Wrigley Field is scheduled to start at 2:20 PM ET.

Conclusion

We predict the Cubs, with a 68% win probability, will likely beat the Nationals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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