Celtics vs. Pistons prediction: Detroit favored to win Monday's NBA matchup [1/19/2026]

NBA action continues on Monday at 8:00 PM ET as the Boston Celtics lock horns with the Detroit Pistons at Little Caesars Arena.

Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Celtics vs. Pistons game.

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature stars like Cade Cunningham, Jalen Duren and Tobias Harris, while the Celtics will be led by Jaylen Brown, Derrick White and Payton Pritchard.

This article offers an expanded analysis of Monday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Celtics vs. Pistons prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Monday's NBA game between the Celtics and Pistons 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Pistons a 59% chance of beating the Celtics. Our predicted final score has the Pistons winning 112-109.

According to our model, the bookmakers have got it right, and the Celtics and Pistons each have a 50% chance of covering the spread, while the over/under total of 223.5 points has a 51% chance of staying under.

Celtics vs. Pistons odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Celtics vs. Pistons picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: