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Red Sox vs. Tigers prediction: Detroit favored to win Tuesday's MLB matchup [5/5/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Boston Red Sox vs Detroit Tigers predictions for MLB Tuesday.
The Detroit Tigers will take on the Boston Red Sox in MLB action at Comerica Park on Tuesday, starting at 6:40 PM ET.
Framber Valdez (2-1, 3.35 ERA) will start for the Tigers, while the Red Sox are going with Jovani Morán (0-0, 2.33 ERA).
Based on updated simulation results, Dimers' proven MLB model projects the Tigers as the most likely winner of the Red Sox vs. Tigers game.
This article offers further insights into Tuesday's matchup, including best bets and picks.
Red Sox vs. Tigers prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Tuesday's MLB matchup between the Red Sox and Tigers, forming part of our MLB predictions coverage.
Our famous predictive model currently gives the Tigers a 62% chance of defeating the Red Sox.
According to our model, the Red Sox (+1.5) have a 55% chance of covering the run line, while the 8-run over/under has a 55% chance of going over.
Red Sox vs. Tigers odds [5/5/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Red Sox | Tigers |
|---|---|---|
| Run Line | +1.5 (-136) | -1.5 (+115) |
| Moneyline | +155 | -180 |
| Total | o8 (-112) | u8 (-108) |
All odds are correct at the time of publication and are subject to change.
Red Sox vs. Tigers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Tigers -1.5 | +115 |
| Moneyline | Red Sox | +155 |
| Total | Over 8 | -112 |
According to our MLB best bets, the top play to make on this game is Over 8 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Red Sox vs. Tigers game-day updates and essential details
Tuesday's MLB game between the Tigers and Red Sox at Comerica Park is scheduled to start at 6:40 PM ET.
- Who: Boston Red Sox vs. Detroit Tigers
- Date: Tuesday, May 5, 2026
- Time: 6:40 PM ET/3:40PM PT
- Venue: Comerica Park
Conclusion
We predict the Tigers, with a 62% win probability, will likely beat the Red Sox in Tuesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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