White Sox vs. Tigers prediction: Detroit favored to win Sunday's MLB matchup [6/21/2026]
Get Chicago White Sox vs Detroit Tigers predictions for MLB Sunday.

The Detroit Tigers will square off with the Chicago White Sox, in what is expected to be a close MLB game, at Comerica Park on Sunday, beginning at 1:40 PM ET.
Keider Montero (3-5, 3.66 ERA) will start on the mound for the Tigers, while the White Sox have opted for Davis Martin (9-3, 3.31 ERA).
Based on the latest simulations, Dimers' proven MLB model gives the Tigers a slight edge with a 54.7% win probability over the White Sox.
This article offers further insights into Sunday's White Sox vs. Tigers matchup, including best bets and picks.
White Sox vs. Tigers prediction: Who will win and cover?
Our leading predictive model currently gives the Tigers a 54.7% chance of defeating the White Sox.
According to our model, the White Sox (+1.5) have a 61.6% chance of covering the run line, while the 8-run over/under has a 55.3% chance of going over,.
White Sox vs. Tigers odds [6/21/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | White Sox | Tigers |
|---|---|---|
| Run Line | +1.5 (-220) | -1.5 (+165) |
| Moneyline | -101 | -116 |
| Total | o8 (-114) | u8 (-105) |
All odds are correct at the time of publication and are subject to change.
White Sox vs. Tigers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Tigers -1.5 | +165 |
| Moneyline | Tigers | -116 |
| Total | Over 8 | -114 |
According to our MLB best bets, the top play to make on this game is Over 8 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
White Sox vs. Tigers game-day updates and essential details
Sunday's MLB matchup between the Tigers and White Sox at Comerica Park is scheduled to start at 1:40 PM ET.
- Who: Chicago White Sox vs. Detroit Tigers
- Date: Sunday, June 21, 2026
- Time: 1:40 PM ET/10:40AM PT
- Venue: Comerica Park
Conclusion
We predict the Tigers, with a 54.7% win probability, will likely beat the White Sox in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



