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Pacers vs. Cavaliers prediction: Cleveland to win, Donovan Mitchell projected for big game in Sunday's NBA matchup [4/5/2026]

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Written by Ryan Leaver

Get Indiana Pacers vs Cleveland Cavaliers predictions for NBA Sunday.

Indiana Pacers-Cleveland Cavaliers Predictions and Game Preview.
Indiana Pacers vs. Cleveland Cavaliers NBA prediction for Sunday, April 5, 2026.

The Cleveland Cavaliers and Indiana Pacers will lock horns in NBA action at Rocket Arena on Sunday, with tipoff at 6:00 PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Cavaliers as the most likely winner of the Pacers vs. Cavaliers game.

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature stars like Donovan Mitchell, James Harden and Max Strus, while the Pacers will look to Quenton Jackson, Jay Huff and Obi Toppin.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pacers vs. Cavs prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Sunday's NBA matchup between the Pacers and Cavaliers, forming part of our NBA predictions coverage.

Our leading predictive model currently gives the Cavaliers an 88% chance of defeating the Pacers. Our predicted final score has the Cavaliers winning 126-112.

According to our model, the Pacers (+16.5) have a 58% chance of covering the spread, while the 240.5-point over/under has a 56% chance of staying under.

 

Pacers vs. Cavaliers odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Pacers Cavaliers
Spread +16.5 (-106) -16.5 (-110)
Moneyline +1000 -1700
Total o240.5 (-105) u240.5 (-112)

All odds are correct at the time of publication and are subject to change.

Pacers vs. Cavaliers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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