Clippers vs. Trail Blazers prediction: Why Portland is favored to win Friday's NBA game [4/10/2026]

NBA action continues on Friday at 10:00 PM ET as the Los Angeles Clippers square off with the Portland Trail Blazers at Moda Center.

Based on the latest simulation results and today’s injury updates, Dimers' proven NBA model predicts the Trail Blazers as the most likely winner of the Clippers vs. Trail Blazers game.

This prediction follows the latest NBA Injury Report, which suggests the Trail Blazers lineup will feature players like Deni Avdija, Jrue Holiday and Shaedon Sharpe, while the Clippers will rely on Kawhi Leonard, Darius Garland and Bennedict Mathurin.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Clippers vs. Blazers prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Friday's NBA matchup between the Clippers and Trail Blazers, forming part of our NBA predictions coverage.

Our famous predictive model currently gives the Trail Blazers a 56% chance of defeating the Clippers. Our predicted final score has the Trail Blazers winning 114-112.

According to our model, the Clippers (+1.5) have a 52% chance of covering the spread, while the 227.5-point over/under has an equal 50-50 chance of hitting.

Clippers vs. Trail Blazers odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Clippers	Trail Blazers
Spread	+1.5 (-105)	-1.5 (-112)
Moneyline	+105	-120
Total	o227.5 (-105)	u227.5 (-115)

All odds are correct at the time of publication and are subject to change.

Clippers vs. Trail Blazers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Clippers +1.5	-105
Moneyline	Trail Blazers	-120
Total	Over 227.5	-105

According to our best NBA bets for Friday, the top play to make on this game is Clippers +1.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Clippers vs. Trail Blazers player props

Looking for LA Clippers vs. Portland NBA prop bets? We use the best information available to project how each team's leading players will perform at Moda Center.

Kawhi Leonard is expected to lead the Clippers with 29 points, 7 rebounds and 4 assists, while Deni Avdija is projected to have 26 points, 7 rebounds and 8 assists for the Trail Blazers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Clippers prediction

Our model's projected player stats for the Clippers are:

Player	PTS	REB	AST	3PM	DFS
Kawhi Leonard	29	7	4	3	51
Darius Garland	20	2	7	3	38
B. Mathurin	14	4	2	1	27
John Collins	13	5	1	1	26
Brook Lopez	12	5	2	2	28

Trail Blazers prediction

Projected points, rebounds, assists and three-pointers made for the Trail Blazers:

Player	PTS	REB	AST	3PM	DFS
Deni Avdija	26	7	8	2	52
Jrue Holiday	18	5	7	3	39
Shaedon Sharpe	16	3	2	2	26
Scoot Henderson	14	3	4	2	29
Toumani Camara	14	5	3	3	30

Clippers vs. Blazers game-day updates and essential details

Friday's action between the Trail Blazers and Clippers at Moda Center is scheduled to commence at 10:00 PM ET.

• Who: Los Angeles Clippers vs. Portland Trail Blazers
• Date: Friday, April 10, 2026
• Time: 10:00 PM ET/7:00PM PT
• Venue: Moda Center

Conclusion

We predict the Trail Blazers, with a 56% win probability, will likely beat the Clippers in Friday's NBA matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.