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Read Article Dodgers vs. Brewers prediction: Why Dodgers are favored to win Friday's MLB matchup [5/22/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Los Angeles Dodgers vs Milwaukee Brewers predictions for MLB Friday.
The Milwaukee Brewers will square off with the Los Angeles Dodgers, in what is expected to be a tight MLB game, at American Family Field on Friday, commencing at 7:40 PM ET.
Logan Henderson (1-1, 3.50 ERA) will get the ball for the Brewers, up against Justin Wrobleski (6-1, 2.49 ERA) for the Dodgers.
Based on the latest simulations, Dimers' proven MLB model gives the Dodgers a slight edge with a 51% win probability over the Brewers.
This article offers a closer look at Friday's Dodgers vs. Brewers matchup, including best bets and picks.
Dodgers vs. Brewers prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the result of Friday's MLB matchup between the Dodgers and Brewers, forming part of our MLB predictions coverage.
Our leading predictive model gives the Dodgers a 51% chance of defeating the Brewers.
According to our model, the Brewers (+1.5) have a 61% chance of covering the run line, while the 8.5-run over/under has a 53% chance of going over.
Dodgers vs. Brewers odds [5/22/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Dodgers | Brewers |
|---|---|---|
| Run Line | -1.5 (+164) | +1.5 (-185) |
| Moneyline | -104 | -110 |
| Total | o8.5 (-102) | u8.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Dodgers vs. Brewers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Dodgers -1.5 | +164 |
| Moneyline | Dodgers | -104 |
| Total | Over 8.5 | -102 |
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Dodgers vs. Brewers game-day updates and essential details
Friday's MLB game between the Brewers and Dodgers at American Family Field is scheduled to start at 7:40 PM ET.
- Who: Los Angeles Dodgers vs. Milwaukee Brewers
- Date: Friday, May 22, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: American Family Field
Conclusion
We predict the Dodgers, with a 51% win probability, will likely beat the Brewers in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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