Dodgers vs. Brewers prediction: Why Dodgers are favored to win Friday's MLB matchup [5/22/2026]

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Written by Dave Garofolo

Get Los Angeles Dodgers vs Milwaukee Brewers predictions for MLB Friday.

Los Angeles Dodgers-Milwaukee Brewers Predictions and Game Preview.
Los Angeles Dodgers vs. Milwaukee Brewers MLB prediction for Friday, May 22, 2026.

The Milwaukee Brewers and Los Angeles Dodgers will lock horns in MLB action at American Family Field on Friday, starting at 7:40 PM ET.

The Brewers will start Logan Henderson (1-1, 3.50 ERA), while the Dodgers have opted for Justin Wrobleski (6-1, 2.49 ERA).

Based on updated simulations, Dimers' advanced MLB model gives the Dodgers a slight edge with a 51% win probability over the Brewers.

This article offers further insights into Friday's Dodgers vs. Brewers matchup, including best bets and picks.

Dodgers vs. Brewers prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Friday's MLB game between the Dodgers and Brewers, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Dodgers a 51% chance of beating the Brewers.

According to our model, the Brewers (+1.5) have a 61% chance of covering the run line, while the over/under total of 8.5 runs has a 53% chance of going over.

 

Dodgers vs. Brewers odds [5/22/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Brewers
Run Line -1.5 (+164) +1.5 (-188)
Moneyline -104 -112
Total o8.5 (-102) u8.5 (-112)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Brewers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Dodgers -1.5 +164
Moneyline Dodgers -104
Total Over 8.5 -102

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Brewers game-day updates and essential details

Friday's MLB game between the Brewers and Dodgers at American Family Field is scheduled to begin at 7:40 PM ET.

Conclusion

We predict the Dodgers, with a 51% win probability, will likely beat the Brewers in Friday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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