Brewers vs. Twins prediction: Why Milwaukee is favored to win Saturday's MLB matchup [5/16/2026]

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Written by Jason Bevilacqua

Get Milwaukee Brewers vs Minnesota Twins predictions for MLB Saturday.

Milwaukee Brewers-Minnesota Twins Predictions and Game Preview.
Milwaukee Brewers vs. Minnesota Twins MLB prediction for Saturday, May 16, 2026.

The Minnesota Twins will square off with the Milwaukee Brewers, in what is expected to be a tight MLB game, at Target Field on Saturday, starting at 7:10 PM ET.

Connor Prielipp (1-1, 3.32 ERA) will start on the mound for the Twins, pitting him against Logan Henderson (0-1, 4.15 ERA) for the Brewers.

Based on the latest simulation results, Dimers' advanced MLB model gives the Brewers a slight edge with a 53% win probability over the Twins.

This article offers a closer look at Saturday's Brewers vs. Twins matchup, including best bets and picks.

Brewers vs. Twins prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Saturday's MLB game between the Brewers and Twins, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Brewers a 53% chance of defeating the Twins.

According to our model, the Twins (+1.5) have a 59% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of going over.

 

Brewers vs. Twins odds [5/16/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Brewers Twins
Run Line -1.5 (+129) +1.5 (-154)
Moneyline -130 +110
Total o8.5 (-102) u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

Brewers vs. Twins picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Twins +1.5 -154
Moneyline Twins +110
Total Over 8.5 -102

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Brewers vs. Twins game-day updates and essential details

Saturday's MLB game between the Twins and Brewers at Target Field is scheduled to commence at 7:10 PM ET.

Conclusion

We predict the Brewers, with a 53% win probability, will likely beat the Twins in Saturday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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