Brewers vs. Twins prediction: Why Milwaukee is favored to win Saturday's MLB matchup [5/16/2026]
Get Milwaukee Brewers vs Minnesota Twins predictions for MLB Saturday.

The Minnesota Twins will square off with the Milwaukee Brewers, in what is expected to be a tight MLB game, at Target Field on Saturday, starting at 7:10 PM ET.
Connor Prielipp (1-1, 3.32 ERA) will start on the mound for the Twins, pitting him against Logan Henderson (0-1, 4.15 ERA) for the Brewers.
Based on the latest simulation results, Dimers' advanced MLB model gives the Brewers a slight edge with a 53% win probability over the Twins.
This article offers a closer look at Saturday's Brewers vs. Twins matchup, including best bets and picks.
Brewers vs. Twins prediction: Who will win and cover?
Our leading predictive model currently gives the Brewers a 53% chance of defeating the Twins.
According to our model, the Twins (+1.5) have a 59% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of going over.
Brewers vs. Twins odds [5/16/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Brewers | Twins |
|---|---|---|
| Run Line | -1.5 (+129) | +1.5 (-154) |
| Moneyline | -130 | +110 |
| Total | o8.5 (-102) | u8.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Brewers vs. Twins picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Twins +1.5 | -154 |
| Moneyline | Twins | +110 |
| Total | Over 8.5 | -102 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Brewers vs. Twins game-day updates and essential details
Saturday's MLB game between the Twins and Brewers at Target Field is scheduled to commence at 7:10 PM ET.
- Who: Milwaukee Brewers vs. Minnesota Twins
- Date: Saturday, May 16, 2026
- Time: 7:10 PM ET/4:10PM PT
- Venue: Target Field
Conclusion
We predict the Brewers, with a 53% win probability, will likely beat the Twins in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



