MLB picks today: Friday's MLB best bets include Cubs vs. Brewers play [6/26/2026]

Cubs ML (+251)

• Edge: 7.7%
• Probability: 36.2%
• Matchup: Cubs vs. Brewers (7:45PM ET)

Our model has identified value on Cubs to defeat Brewers at +251 odds. A 36.2% probability produces an edge of 7.7%, making this the strongest play for today's MLB slate.

Dodgers vs. Padres Over 7.5 runs (-104)

• Edge: 6.8%
• Probability: 57.8%
• Matchup: Dodgers vs. Padres (9:45PM ET)

Dodgers vs. Padres over 7.5 runs carries a 6.8% edge and a probability of 57.8% at -104 odds, according to our model.

Rockies vs. Twins Over 9.5 runs (+120)

• Edge: 6.2%
• Probability: 51.7%
• Matchup: Rockies vs. Twins (8:10PM ET)

Rockies vs. Twins Over 9.5 runs at +120 odds shows a 6.2% edge, supported by a 51.7% probability in simulations.

Cubs +1.5 (+115)

• Edge: 6.1%
• Probability: 52.6%
• Matchup: Cubs vs. Brewers (7:45PM ET)

A 6.1% edge and 52.6% probability makes Cubs +1.5 vs. Brewers a value play in the Cubs vs. Brewers matchup, per our model.

Cubs vs. Brewers Over 7.5 runs (+111)

• Edge: 5.7%
• Probability: 53.2%
• Matchup: Cubs vs. Brewers (7:45PM ET)

Cubs vs. Brewers Over 7.5 runs at +111 odds presents a 5.7% edge, with simulations resulting in a probability of 53.2%.

Braves vs. Giants Over 7.5 runs (-108)

• Edge: 5.0%
• Probability: 57%
• Matchup: Braves vs. Giants (10:15PM ET)

Our model finds value on Over 7.5 runs in Braves vs. Giants at -108 odds, supported by an edge of 5.0%.

Mariners vs. Guardians Over 7.5 runs (+106)

• Edge: 4.8%
• Probability: 53.3%
• Matchup: Mariners vs. Guardians (7:10PM ET)

Our model has uncovered value on Mariners vs. Guardians Over 7.5 runs at +106 odds. A 53.3% probability produces a 4.8% edge, making this a strong play for today's MLB action.

Astros vs. Tigers Over 8.5 runs (+102)

• Edge: 4.7%
• Probability: 54.2%
• Matchup: Astros vs. Tigers (6:40PM ET)

A 4.7% edge on a 54.2% probability makes Over 8.5 runs at +102 odds a solid value play in today's Astros vs. Tigers matchup.

Athletics vs. AngelsOver 8.5 runs (-106)

• Edge: 4.7%
• Probability: 56.2%
• Matchup: Athletics vs. Angels (9:38PM ET)

Our model projects value on Over 8.5 runs at -106 odds. A 56.2% probability produces a 4.7% edge, making the Over the favorable side in today's matchup.

Royals vs. White Sox Over 8.5 runs (+108)

• Edge: 4.2%
• Probability: 52.2%
• Matchup: Royals vs. White Sox (7:40PM ET)

Rounding out our top 10 bets, Royals vs. White Sox Over 8.5 runs at +108 odds shows a 52.2% probability and a 4.2% edge.

MLB best bets summary: Friday, 6/26/2026

As of 8:09AM ET, here are our top MLB bets by edge recommended by our model:

List of upcoming MLB games to bet on [6/26/2026]

• Astros vs. Tigers (6:40PM ET, Friday)
• Reds vs. Pirates (6:40PM ET, Friday)
• Nationals vs. Orioles (7:05PM ET, Friday)
• Rangers vs. Blue Jays (7:07PM ET, Friday)
• Mariners vs. Guardians (7:10PM ET, Friday)
• Yankees vs. Red Sox (7:10PM ET, Friday)
• D-Backs vs. Rays (7:10PM ET, Friday)
• Royals vs. White Sox (7:40PM ET, Friday)
• Cubs vs. Brewers (7:45PM ET, Friday)
• Rockies vs. Twins (8:10PM ET, Friday)
• Marlins vs. Cardinals (8:15PM ET, Friday)
• Athletics vs. Angels (9:38PM ET, Friday)
• Dodgers vs. Padres (9:45PM ET, Friday)
• Braves vs. Giants (10:15PM ET, Friday)

Conclusion

Our MLB best bets are locked and loaded for June 26, 2026, featuring plays such as Cubs ML vs. Brewers and over 7.5 runs in the Dodgers vs. Padres matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.