May 25, 2026
Rays vs. Orioles prediction: Baltimore favored to win Monday's MLB matchup [5/25/2026]
Read Article MLB picks today: Memorial Day MLB best bets include Astros vs. Rangers play [5/25/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get MLB picks today and best bets for Monday, May 25, 2026.
Today’s MLB picks for Memorial Day are here, with Astros vs. Rangers and Diamondbacks vs. Giants among the top plays identified by our model across Monday’s MLB action.
Dimers’ predictive analytics engine runs 24/7, scanning the latest baseball odds to find top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of MLB best bets today [5/25, updated 3:46PM ET]
Below, you’ll find today’s best baseball bets, ranked by edge for Monday, May 25, 2026.
Astros vs. Rangers over 7.5 runs (-111)
- Edge: 8.9%
- Probability: 61.4%
- Matchup: Astros vs. Rangers (7:05PM ET, Monday)
Our model has identified value on over 7.5 runs in Astros vs. Rangers at -111 odds. A 61.4% probability produces an edge of 8.9%, making this the strongest play for today's MLB slate.
Diamondbacks vs. Giants over 7.5 runs (-106)
- Edge: 4.2%
- Probability: 55.7%
- Matchup: Diamondbacks vs. Giants (5:05PM ET, Monday)
Diamondbacks vs. Giants over 7.5 runs carries a 4.2% edge and a probability of 55.7% at -106 odds, according to our model.
Reds vs. Mets over 7.5 runs (+106)
- Edge: 4.0%
- Probability: 52.5%
- Matchup: Reds vs. Mets (4:10PM ET, Monday)
Reds vs. Mets over 7.5 runs at +106 odds shows a 4.0% edge, supported by a 52.5% probability in simulations.
Phillies vs. Padres over 7.5 runs (+120)
- Edge: 3.9%
- Probability: 49.4%
- Matchup: Phillies vs. Padres (6:40PM ET, Monday)
A 3.9% edge and 49.4% probability make Phillies vs. Padres over 7.5 runs at a value play in the Phillies vs. Padres matchup, per our model.
Rockies vs. Dodgers over 8.5 runs (-111)
- Edge: 3.6%
- Probability: 56.1%
- Matchup: Rockies vs. Dodgers (9:10PM ET, Monday)
Rockies vs. Dodgers over 8.5 runs at -111 odds presents a 3.6% edge, with simulations resulting in a probability of 56.1%.
Nationals vs. Guardians over 8.5 runs (+111)
- Edge: 2.9%
- Probability: 50.4%
- Matchup: Nationals vs. Guardians (6:10PM ET, Monday)
Our model finds value on over 8.5 runs in Nationals vs. Guardians at +111 odds, supported by an edge of 2.9%.
Marlins vs. Blue Jays over 7.5 runs (-106)
- Edge: 2.7%
- Probability: 54.2%
- Matchup: Marlins vs. Blue Jays (7:07PM ET, Monday)
Our model has uncovered value on Marlins vs. Blue Jays over 7.5 runs at -106 odds. A 54.2% probability produces a 2.7% edge, making this a strong play for today's MLB action.
MLB best bets summary: Monday, 5/25/2026
As of 3:46PM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Astros vs. Rangers | Over 7.5 Runs | -111 @ Polymarket | 8.9% | 61.4% |
| Diamondbacks vs. Giants | Over 7.5 Runs | -106 @ Polymarket | 4.2% | 55.7% |
| Reds vs. Mets | Over 7.5 Runs | +106 @ Polymarket | 4.0% | 52.5% |
| Phillies vs. Padres | Over 7.5 Runs | +120 @ Polymarket | 3.9% | 49.4% |
| Rockies vs. Dodgers | Over 8.5 Runs | -111 @ Polymarket | 3.6% | 56.1% |
| Nationals vs. Guardians | Over 8.5 Runs | +111 @ Polymarket | 2.9% | 50.4% |
| Marlins vs. Blue Jays | Over 7.5 Runs | -106 @ Polymarket | 2.7% | 54.2% |
List of upcoming MLB games to bet on [5/25/2026]
- Reds vs. Mets (4:10PM ET, Monday)
- D-Backs vs. Giants (5:05PM ET, Monday)
- Nationals vs. Guardians (6:10PM ET, Monday)
- Phillies vs. Padres (6:40PM ET, Monday)
- Astros vs. Rangers (7:05PM ET, Monday)
- Marlins vs. Blue Jays (7:07PM ET, Monday)
- Rockies vs. Dodgers (9:10PM ET, Monday)
- Mariners vs. Athletics (9:40PM ET, Monday)
Conclusion
Our MLB best bets are locked and loaded for May 25, 2026, featuring plays such as over 7.5 runs in the Astros vs. Rangers matchup and over 7.5 runs in the Diamondbacks vs. Giants matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are based on current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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