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MLS predictions: Using data to predict scores on opening weekend

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Written by Dave Garofolo
Reviewed by Nick Slade

The MLS returns to action this weekend to kick off the 2026 season and we've used the Dimers data to find the most likely correct score results across all matches.

MLS soccer predictions and scorelines
What does the data say about the most likely scores in opening weekend of MLS?

Major League Soccer returns on Saturday, February 21 to kick off the 2026 season and Dimers MLS predictions are ready for the first set of matches, from our best MLS bets to predicted scorelines for every match and the best picks to win the MLS Cup.

All season long, every week, Dimers’ data-driven algorithms simulate every MLS contest thousands of times, processing 1,000s of inputs across expected-goals metrics, rosters, recent form, and player-level data to predict the most likely scorelines over a full match.


These scores can be utilized in a variety of ways, from betting on longshot results to engineering Both Teams to Score probabilities.

Focusing on outright victories rather than draws, three particular scorelines have emerged with the highest probabilities in MLS this weekend, each at 11% in their respective match, and each getting fair odds by the Dimers model.

For the opening weekend slate, these strong correct-score probabilities come from these three Saturday matches:

⚽ Vancouver vs. Salt Lake

⚽ Philadelphia vs. D.C. United

⚽ Montreal vs. San Diego FC

Here is why the data points toward these specific outcomes for the upcoming fixtures.

MLS Opening Weekend score predictions

Vancouver 2-0 vs. Salt Lake (11% probability)

The model’s strongest single outcome in this matchup points toward a comfortable Vancouver home victory, with every other top scoreline also favoring the Whitecaps.

The data case: The algorithm gives Salt Lake just a 14% chance to win and 19% to draw, indicating a low attacking expectation from the visitors and strong defensive control from Vancouver.

Why the algorithm picked it: Vancouver enter the season as legitimate MLS Cup contenders after last year’s finals run and dominant goal differential, and they also won both meetings with Salt Lake in 2025. At home and priced as clear favorites, the Whitecaps project to control possession and chances, while Salt Lake, longshot title hopefuls, look unlikely to generate enough offense to respond.

At +800 odds, this bet is right in line with our 11% probability.

MORE: Vancouver vs. Salt Lake MLS predictions

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To give you the most accurate and helpful information, this article has been reviewed and edited by Nick Slade through our fact-checking process.
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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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