San Jose Earthquakes vs. Orlando City prediction, odds, MLS picks [7/22/2026]
Get San Jose Earthquakes vs Orlando City predictions for MLS Wednesday.

MLS action continues on Wednesday at 10:30 PM ET as Orlando takes on San Jose at PayPal Park.
Based on the latest simulation results, Dimers' advanced MLS model projects San Jose as the most likely winner of the San Jose vs. Orlando game.
This article offers an expanded analysis of Wednesday's match, including best bets and picks.
San Jose Earthquakes vs. Orlando City prediction: Who will win?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLS matchup between San Jose and Orlando, forming part of our MLS predictions coverage.
Our famous predictive model suggests a 67.2% chance of San Jose winning, a 16.1% chance for Orlando, and a 16.7% chance of a draw.
San Jose Earthquakes vs. Orlando City odds
We have researched the best MLS odds in America for this game, which are listed here:
Moneyline
| Market | San Jose | Orlando | Draw |
|---|---|---|---|
| Moneyline | -179 | +420 | +380 |
All odds are correct at the time of publication and are subject to change.
San Jose Earthquakes vs. Orlando City picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Moneyline: San Jose @ -179 via ESPN BET
According to our best MLS bets, the top play to make on this game is San Jose to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
San Jose Earthquakes vs. Orlando City: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 2-1 San Jose win being the most probable:
| Final Score | Probability |
|---|---|
| SJE 2-1 ORL | 8.7% |
| SJE 3-1 ORL | 7.8% |
| SJE 2-0 ORL | 6.7% |
San Jose Earthquakes vs. Orlando City game-day updates and essential details
Wednesday's game between San Jose and Orlando in MLS at PayPal Park is scheduled to commence at 10:30 PM ET.
- Who: San Jose Earthquakes vs. Orlando City
- Date: Wednesday, July 22, 2026
- Time: 10:30 PM ET/7:30PM PT
- Venue: PayPal Park
Conclusion
According to our computer model, San Jose has a 67.2% win probability on Wednesday, Orlando has a 16.1% win probability, and there is a 16.7% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



