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Read Article Inter Miami vs. Chicago Fire prediction, odds, MLS picks [7/22/2026]
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Written by Nick Slade, Chief Content Officer
Get Inter Miami vs Chicago Fire predictions for MLS Wednesday.
Miami will square off with Chicago in MLS action at Nu Stadium on Wednesday, commencing at 7:30 PM ET.
Based on updated simulation results, Dimers' proven MLS model predicts Miami as the most likely winner of the Miami vs. Chicago game.
This article offers an expanded analysis of Wednesday's match, including best bets and picks.
Inter Miami vs. Chicago Fire prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Wednesday's MLS matchup between Miami and Chicago, forming part of our MLS predictions coverage.
Our leading predictive model suggests a 57.3% chance of Miami winning, a 23.6% chance for Chicago, and a 19.1% chance of a draw.
Additionally, the 2.5-goal over/under has a 75.7% chance of going over, according to our model.
Inter Miami vs. Chicago Fire odds
We have sourced the best MLS odds in America for this game, which are listed here:
Moneyline
| Miami | Chicago | Draw |
|---|---|---|
| +120 | +200 | +310 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -300 | +240 |
All odds are correct at the time of publication and are subject to change.
Inter Miami vs. Chicago Fire picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Moneyline: Miami @ +120 via Bet365
- Total Goals: Over 2.5 @ -300 via Bet365
According to our MLS best bets, the top play to make on this game is Miami to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Inter Miami vs. Chicago Fire: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 2-1 Miami win being the most probable:
| Final Score | Probability |
|---|---|
| MIA 2-1 CHI | 8.6% |
| MIA 1-1 CHI | 7.1% |
| MIA 3-1 CHI | 7% |
Inter Miami vs. Chicago Fire game-day updates and essential details
Wednesday's game between Miami and Chicago in MLS at Nu Stadium is scheduled to start at 7:30 PM ET.
- Who: Inter Miami vs. Chicago Fire
- Date: Wednesday, July 22, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Nu Stadium
Conclusion
According to our computer model, Miami has a 57.3% win probability on Wednesday, Chicago has a 23.6% win probability, and there is a 19.1% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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