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NBA Playoffs picks today: Tuesday's best bets include 76ers vs. Celtics play [4/21/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get best NBA picks today and best bets for Tuesday, April 21, 2026.
Today’s NBA picks for April 21, 2026 are here, with 76ers vs. Celtics and Rockets vs. Lakers among the top plays identified by our model across Tuesday’s NBA playoffs play.
Dimers’ predictive analytics engine runs 24/7, scanning the latest basketball odds to unearth legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of NBA playoffs picks tonight [4/21, updated 7:02AM ET]
Below, you’ll find today’s best basketball bets, ranked by edge for Tuesday, April 21, 2026.
76ers +13.5 (-105)
- Edge: 3.7%
- Probability: 54.9%
- Matchup: 76ers vs. Celtics (7:00PM ET, Tuesday)
Our model has identified value on 76ers +13.5 at -105 odds. A 54.9% probability produces an edge of 3.7%, making this the strongest play for today's NBA slate.
Lakers +4.5 (-105)
- Edge: 2.8%
- Probability: 54%
- Matchup: Rockets vs. Lakers (10:30PM ET, Tuesday)
Lakers +4.5 carries a 2.8% edge and a probability of 54% at -105 odds, according to our model.
76ers ML (+660)
- Edge: 2.1%
- Probability: 15.2%
- Matchup: 76ers vs. Celtics (7:00PM ET, Tuesday)
76ers ML at +660 odds shows a 2.1% edge, supported by a 15.2% probability in simulations.
NBA Playoffs best bets summary: Tuesday, 4/21/2026
As of 7:02AM ET, here are our top NBA bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| 76ers vs. Celtics | 76ers +13.5 | -105 @ BetMGM | 3.7% | 54.9% |
| Rockets vs. Lakers | Lakers +4.5 | -105 @ DraftKings | 2.8% | 54% |
| 76ers vs. Celtics | 76ers ML | +660 @ FanDuel | 2.1% | 15.2% |
List of upcoming NBA playoffs games to bet on [4/21/2026]
- 76ers vs. Celtics (7:00PM ET, Tuesday)
- Trail Blazers vs. Spurs (8:00PM ET, Tuesday)
- Rockets vs. Lakers (10:30PM ET, Tuesday)
Conclusion
Our NBA best bets are locked and loaded for April 21, 2026, featuring plays such as 76ers +13.5 and Lakers +4.5. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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