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Knicks vs. Grizzlies prediction: Why New York is favored to win Wednesday's NBA matchup [4/1/2026]

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Written by Jason Bevilacqua

Get New York Knicks vs Memphis Grizzlies predictions for NBA Wednesday.

New York Knicks-Memphis Grizzlies Predictions and Game Preview.
New York Knicks vs. Memphis Grizzlies NBA prediction for Wednesday, April 1, 2026.

The Memphis Grizzlies will take on the favored New York Knicks in NBA action at FedExForum on Wednesday, commencing at 8:00 PM ET.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model predicts the Knicks as the most likely winner of the Knicks vs. Grizzlies game.

This prediction follows the latest NBA Injury Report, which suggests the Grizzlies lineup will feature stars like GG Jackson, Cedric Coward and Javon Small, while the Knicks will rely on Karl-Anthony Towns, OG Anunoby and Mikal Bridges.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Knicks vs. Grizzlies prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NBA matchup between the Knicks and Grizzlies, forming part of our NBA predictions coverage.

Our leading predictive model currently gives the Knicks an 85% chance of beating the Grizzlies. Our predicted final score has the Knicks winning 118-106.

According to our model, the Grizzlies (+13.5) have a 56% chance of covering the spread, while the over/under total of 224.5 points has an equal 50-50 chance of hitting.

 

Knicks vs. Grizzlies odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Knicks Grizzlies
Spread -13.5 (-112) +13.5 (-105)
Moneyline -900 +610
Total o224.5 (-115) u224.5 (-105)

All odds are correct at the time of publication and are subject to change.

Knicks vs. Grizzlies picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Grizzlies +13.5 -105
Moneyline Grizzlies +610
Total Under 224.5 -105

According to our best NBA bets for Wednesday, the top play to make on this game is Grizzlies +13.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Knicks vs. Grizzlies player props

Looking for New York vs. Memphis NBA player props? We have crunched the numbers to project how each team's leading players will perform at FedExForum.

Karl-Anthony Towns is expected to lead the Knicks with 22 points, 13 rebounds and 3 assists, while GG Jackson is projected to have 13 points, 4 rebounds and 2 assists for the Grizzlies.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Knicks prediction

Our model's projected player stats for the Knicks are:

Player PTS REB AST 3PM DFS
K. Towns 22 13 3 2 48
OG Anunoby 19 6 3 2 36
Mikal Bridges 16 4 4 2 32
Josh Hart 14 8 6 1 36
Jordan Clarkson 11 2 2 1 18

Grizzlies prediction

Projected points, rebounds, assists and three-pointers made for the Grizzlies:

Player PTS REB AST 3PM DFS
GG Jackson 13 4 2 1 25
Cedric Coward 12 5 3 1 27
Javon Small 12 3 4 2 28
O. Prosper 11 4 1 1 23
Cam Spencer 10 3 6 2 26

Knicks vs. Grizzlies game-day updates and essential details

Wednesday's game between the Grizzlies and Knicks at FedExForum is scheduled to begin at 8:00 PM ET.

Conclusion

We predict the Knicks, with an 85% win probability, will likely beat the Grizzlies on Wednesday, with Karl-Anthony Towns projected for a game-high 48 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Grizzlies insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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