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Osasuna vs. Real Madrid prediction, odds, La Liga picks [2/21/2026]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get Osasuna vs Real Madrid predictions for La Liga Saturday.
Osasuna will square off with Real Madrid in La Liga action at Estadio El Sadar on Saturday, beginning at 12:30 PM ET.
Based on updated simulation results, Dimers' advanced La Liga model predicts Real Madrid as the most likely winner of the Osasuna vs. Real Madrid game.
This article offers an expanded analysis of Saturday's matchup, including best bets and picks.
Osasuna vs. Real Madrid prediction: Who will win?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's La Liga match between Osasuna and Real Madrid 10,000 times as part of our La Liga predictions coverage.
Our leading predictive model currently suggests a 23.1% chance of Osasuna winning, a 53.6% chance for Real Madrid, and a 23.3% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 55% chance of going over, according to our model.
Osasuna vs. Real Madrid odds
We have researched the best La Liga odds in America for this game, which are listed here:
Moneyline
| Osasuna | Real Madrid | Draw |
|---|---|---|
| +390 | -140 | +310 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -144 | +118 |
All odds are correct at the time of publication and are subject to change.
Osasuna vs. Real Madrid picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Osasuna | +390 |
| Total Goals | Under 2.5 | +118 |
According to our best La Liga bets, the top play to make on this game is Osasuna to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Osasuna vs. Real Madrid: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| OSA 1-1 MAD | 11% |
| OSA 0-1 MAD | 10.1% |
| OSA 1-2 MAD | 9.8% |
When it comes to the both teams to score (BTTS) market, we project a 55.2% chance of the yes hitting, and a 44.8% probability of at least one team keeping a clean sheet.
These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.
Osasuna vs. Real Madrid game-day updates and essential details
Saturday's La Liga matchup between Osasuna and Real Madrid at Estadio El Sadar is scheduled to start in the USA at 12:30 PM ET.
- Who: Osasuna vs. Real Madrid
- Date: Saturday, February 21, 2026
- Time: 12:30 PM ET/9:30AM PT
- Venue: Estadio El Sadar
Conclusion
According to our computer model, Osasuna has a 23.1% win probability on Saturday, Real Madrid has a 53.6% win probability, and there is a 23.3% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Osasuna vs. Real Madrid insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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