Mariners vs. Astros prediction: Close contest projected after new data released for Thursday's MLB matchup [5/14/2026]
Get Seattle Mariners vs Houston Astros predictions for MLB Thursday.

The Houston Astros will take on the Seattle Mariners, in what is expected to be a tight MLB game, at Daikin Park on Thursday, beginning at 2:10 PM ET.
The Astros will start Mike Burrows (2-4, 5.04 ERA), up against Luis Castillo (0-4, 6.57 ERA) for the Mariners.
Based on the latest simulation results, Dimers' advanced MLB model gives an equal chance for both both teams to win the Mariners-Astros matchup.
This article offers a closer look at Thursday's Mariners vs. Astros matchup, including best bets and picks.
Mariners vs. Astros prediction: Who will win and cover?
Our famous predictive model can't split the two teams, giving both the Mariners and Astros a 50% chance of winning the game.
According to our model, the Astros (+1.5) have a 61% chance of covering the run line, while the 9-run over/under has a 54% chance of going over.
Mariners vs. Astros odds [5/14/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Mariners | Astros |
|---|---|---|
| Run Line | -1.5 (+146) | +1.5 (-170) |
| Moneyline | -112 | -102 |
| Total | o9 (-108) | u9 (-109) |
All odds are correct at the time of publication and are subject to change.
Mariners vs. Astros picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | -170 |
| Moneyline | Astros | -102 |
| Total | Over 9 | -108 |
According to our MLB best bets, the top play to make on this game is Over 9 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Mariners vs. Astros game-day updates and essential details
Thursday's MLB action between the Astros and Mariners at Daikin Park is scheduled to begin at 2:10 PM ET.
- Who: Seattle Mariners vs. Houston Astros
- Date: Thursday, May 14, 2026
- Time: 2:10 PM ET/11:10AM PT
- Venue: Daikin Park
Conclusion
We predict a close game between the Mariners and Astros on Thursday, with each team having a 50% chance of winning.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



