Blue Jays vs. Yankees prediction: Yankees favored to win Wednesday's MLB matchup [5/20/2026]
Get Toronto Blue Jays vs New York Yankees predictions for MLB Wednesday.

The New York Yankees will face the Toronto Blue Jays in MLB action at Yankee Stadium on Wednesday, starting at 7:05 PM ET.
The Yankees will have Cam Schlittler (6-1, 1.35 ERA) as their starting pitcher, while the Blue Jays will counter with Trey Yesavage (1-1, 1.40 ERA).
Based on the latest simulation results, Dimers' proven MLB model predicts the Yankees as the most likely winner of the Blue Jays vs. Yankees game.
This article offers further insights into Wednesday's matchup, including best bets and picks.
Blue Jays vs. Yankees prediction: Who will win and cover?
Our famous predictive model currently gives the Yankees a 60% chance of defeating the Blue Jays.
According to our model, the Blue Jays (+1.5) have a 57% chance of covering the run line, while the over/under total of 7.5 runs has a 56% chance of going over.
Blue Jays vs. Yankees odds [5/20/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Blue Jays | Yankees |
|---|---|---|
| Run Line | +1.5 (-144) | -1.5 (+125) |
| Moneyline | +145 | -165 |
| Total | o7.5 (-104) | u7.5 (-102) |
All odds are correct at the time of publication and are subject to change.
Blue Jays vs. Yankees picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Blue Jays +1.5 | -144 |
| Moneyline | Blue Jays | +145 |
| Total | Over 7.5 | -104 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Blue Jays vs. Yankees game-day updates and essential details
Wednesday's MLB game between the Yankees and Blue Jays at Yankee Stadium is scheduled to begin at 7:05 PM ET.
- Who: Toronto Blue Jays vs. New York Yankees
- Date: Wednesday, May 20, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 60% win probability, will likely beat the Blue Jays in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



