Dodgers vs. Phillies prediction: Why Dodgers are favored to win Wednesday's MLB matchup [7/22/2026]

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Written by Dave Garofolo

Get Los Angeles Dodgers vs Philadelphia Phillies predictions for MLB Wednesday.

Los Angeles Dodgers-Philadelphia Phillies Predictions and Game Preview.
Los Angeles Dodgers vs. Philadelphia Phillies MLB prediction for Wednesday, July 22, 2026.

The Philadelphia Phillies and Los Angeles Dodgers are scheduled to meet in MLB action at Citizens Bank Park on Wednesday, starting at 6:40 PM ET.

The Phillies will have Aaron Nola (3-7, 5.68 ERA) as their starting pitcher, up against Eric Lauer (4-5, 4.81 ERA) for the Dodgers.

Based on the latest simulation results, Dimers' advanced MLB model gives the Dodgers a slight edge with a 53.2% win probability over the Phillies.

This article offers an expanded analysis of Wednesday's Dodgers vs. Phillies matchup, including best bets and picks.

Dodgers vs. Phillies prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's MLB matchup between the Dodgers and Phillies, forming part of our MLB predictions coverage.

Our famous predictive model currently gives the Dodgers a 53.2% chance of beating the Phillies.

According to our model, the Phillies (+1.5) have a 56.6% chance of covering the run line, while the over/under total of 9.5 runs has a 51.3% chance of going over,.

 

Dodgers vs. Phillies odds [7/22/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Phillies
Run Line -1.5 (+138) +1.5 (-144)
Moneyline -108 +106
Total o9.5 (+104) u9.5 (-106)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Phillies picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Dodgers -1.5 +138
Moneyline Dodgers -108
Total Over 9.5 +104

According to our MLB best bets, the top play to make on this game is Over 9.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Phillies game-day updates and essential details

Wednesday's MLB game between the Phillies and Dodgers at Citizens Bank Park is scheduled to commence at 6:40 PM ET.

Conclusion

We predict the Dodgers, with a 53.2% win probability, will likely beat the Phillies in Wednesday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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