Padres vs. Cubs prediction: Close contest projected after new data released for Game 3 of 2025 Wild Card Series

The Chicago Cubs and San Diego Padres are scheduled to meet in Game 3 of their Wild Card Series at Wrigley Field on Thursday, starting at 5:08PM ET.

Jameson Taillon (0-0, 0.00 ERA) will start for the Cubs, up against Yu Darvish (0-0, 0.00 ERA) for the Padres.

Based on the latest simulation results, Dimers' advanced MLB model projects an equal chance for both the Cubs and Padres to win today's game.

For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Padres vs. Cubs predictions page.

Padres vs. Cubs prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Padres and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently can't split the two teams, giving both the Padres and Cubs a 50% chance of winning the game.

According to our model, the 7.5-run over/under has a 64% chance of going over.

Padres vs. Cubs odds [Wild Card Series Game 3]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Cubs
Moneyline	-102	-115
Total	o7.5 (-110)	u7.5 (-108)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Cubs picks and best bets

Our model's strongest edge in today's Padres vs. Cubs matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Padres vs. Cubs game-day updates and essential details

Thursday's MLB action between the Cubs and Padres at Wrigley Field is scheduled to commence at 5:08PM ET.

• Who: San Diego Padres vs. Chicago Cubs
• Date: Thursday, October 2, 2025
• Time: 5:08PM ET/2:08PM PT
• Venue: Wrigley Field

Dimers' comprehensive preview of Thursday's Padres vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict a close game between the Padres and Cubs on Thursday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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