Blue Jays vs. Yankees prediction: Yankees favored to win Game 4 of ALDS [10/8/2025]

The New York Yankees will take on the Toronto Blue Jays in Game 4 of the American League Division Series at Yankee Stadium on Wednesday, beginning at 7:08PM ET.

The Yankees will send Cam Schlittler (1-0, 0.00 ERA in 2025 postseason) to the mound, while the Blue Jays are going with Louis Varland (0-1, 6.75 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Yankees as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Blue Jays-Yankees game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Yankees' chance of winning at 61%, with the Blue Jays at 39%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Yankees predictions page.

Blue Jays vs. Yankees prediction: Who will win Game 4?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's MLB game between the Blue Jays and Yankees 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Yankees a 61% chance of beating the Blue Jays.

According to our model, the Blue Jays (+1.5) have a 56% chance of covering the run line, while the 8.5-run over/under has a 63% chance of going over.

Blue Jays vs. Yankees Game 4 odds [10/8/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Yankees
Run Line	+1.5 (-140)	-1.5 (+118)
Moneyline	+150	-172
Total	o8.5 (-105)	u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Blue Jays vs. Yankees picks and best bets for Game 4

Our model's strongest edge in today's Blue Jays vs. Yankees matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Blue Jays vs. Yankees game-day updates and essential details

Wednesday's MLB matchup between the Yankees and Blue Jays at Yankee Stadium is scheduled to commence at 7:08PM ET.

• Who: Toronto Blue Jays vs. New York Yankees
• Date: Wednesday, October 8, 2025
• Time: 7:08PM ET/4:08PM PT
• Venue: Yankee Stadium

Dimers' comprehensive preview of Wednesday's Blue Jays vs. Yankees matchup includes our prediction, picks and the latest betting odds.

Before making any Blue Jays vs. Yankees picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Yankees, with a 61% win probability, will likely beat the Blue Jays on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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