Cruz Azul vs. Guadalajara prediction, odds, Liga MX picks [5/13/2026]

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's Liga MX game between Cruz Azul and Guadalajara, forming part of our Liga MX predictions coverage.

Our independent predictive model indicates a 49.5% chance of Cruz Azul winning, a 25.3% chance for Guadalajara, and a 25.3% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 52% chance of staying under, according to our model.

Cruz Azul vs. Guadalajara odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Cruz Azul	Guadalajara	Draw
+110	+250	+250

Total Goals

Over 2.5	Under 2.5
-115	-120

All odds are correct at the time of publication and are subject to change.

Cruz Azul vs. Guadalajara picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Moneyline	Cruz Azul	+110
Total Goals	Under 2.5	-120

According to our Liga MX best bets, the top play to make on this game is Cruz Azul to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Cruz Azul vs. Guadalajara: Correct score and BTTS predictions

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

Final Score	Probability
CAZ 1-1 GUA	12%
CAZ 1-0 GUA	11.5%
CAZ 2-1 GUA	9.4%

When it comes to the both teams to score (BTTS) market, we project a 51.3% chance of both Cruz Azul and Guadalajara finding the net and a 48.7% chance that at least one doesn’t.

These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.

Cruz Azul vs. Guadalajara game-day updates and essential details

Wednesday's game between Cruz Azul and Guadalajara is scheduled to begin at 10:00 PM ET.

• Who: Cruz Azul vs. Guadalajara
• Date: Wednesday, May 13, 2026
• Time: 10:00 PM ET/7:00PM PT

Conclusion

According to our computer model, Cruz Azul has a 49.5% win probability on Wednesday, Guadalajara has a 25.3% win probability, and there is a 25.3% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.