Cubs vs. Diamondbacks: MLB Prediction & Analysis

Our detailed prediction and analysis for the Cubs vs. Diamondbacks MLB game on Tuesday, August 25, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
MLB
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MLB sport icon
MLB
Cubs
Clay Holmes 5-6, 2.49 ERA
vs.
Chase Field
D-Backs
Brandon Pfaadt 7-1, 3.39 ERA
Chase Field
Pre-Game Probabilities Last Update:

Moneyline

Moneyline
Win %
  • Cubs
    49.2%
    Hard Rock BetHard Rock Bet
  • D-Backs
    50.8%
    PolymarketPolymarket
Weather Forecast
Last Updated: August 25, 2026, 7:50 AM ET
Sunny weather icon
109°FSunny
  • RoofRetractable
  • Humidity11%
  • Wind speed6mph
  • Cloud cover5%
  • Dew point43°F
  • Wind directionWNW

Cubs vs. Diamondbacks: Detailed Breakdown

Matchup overview: MLB Tuesday

  • Teams: CHI Cubs Cubs vs. Arizona Diamondbacks
  • Date: Tuesday, August 25, 2026
  • Time: 9:40PM ET
  • Venue: Chase Field

Current betting odds

  • Spread: Cubs (-1.5, +160), Diamondbacks (+1.5, -163)
  • Moneyline: Cubs -104, Diamondbacks +104
  • Total (Over/Under): 8.5 runs (+111/-108)

Dimers’ win probabilities

  • Cubs: 49.4%
  • Diamondbacks: 50.6%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 49.4%, while the Diamondbacks have a win probability of 50.6%.

Summary

According to our analysis, the Diamondbacks are more likely to beat the Cubs in the MLB game at Chase Field on Tuesday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Diamondbacks predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.